Kajian aktivitas antibakteri dari ekstrak etanol dan fraksi genus angelica terhadap berbagai bakteri

Baraja, Melissa (2020) Kajian aktivitas antibakteri dari ekstrak etanol dan fraksi genus angelica terhadap berbagai bakteri. Skripsi thesis, Universitas Setia Budi.

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Abstract

Genus Angelica plants for example ashitaba used as traditional medicine and contained chemical coumpouds as alkaloids, saponins, tannins, and flavonoids that are believed to have antibacterial activity. The purpose of this study was to determine activity of ethanolic extract and fraction genus Angelica as antibacterial against various bacteria. Ashitaba powder was extract with ethanol 70% by maceration method. Extract was collected and fractionated with n-hexane, ethyl acetate and water. The yield of ethanolic extract was 16,77%. The results of antibacterial activity data were obtained by literature review which showed ethanol extract and fraction genus Angelica against various bacteria had antibacterial activity. Based on the literature review, the diffusion method of ethyl acetate fraction with a concentration of 40% from Angelica keiskei leaves, has the most active antibacterial activity against Staphylococcus aureus with an inhibitory diameter of 20.5 mm. In the dilution method of ethanol extract from Angelica keiskei stems, the MIC value of 6% -8% was obtained against Mycobacterium tuberculosis and ethyl acetate fraction from Angelica keiskei, obtained KBM values of 10% against Staphylococcus aureus and Salmonella thypi. Keywords: Antibacterial; ashitaba; Angelica; fraction; bacteria

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Antibacterial; ashitaba; Angelica; fraction; bacteria
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	13 Jun 2022 06:52
Last Modified:	13 Jun 2022 06:52
URI:	http://repo.setiabudi.ac.id/id/eprint/4848

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