FORMULASI SEDIAAN SERUM EKSTRAK ETANOL DAUN UBI JALAR UNGU (Ipomoea batatas (L.) Lamk) SEBAGAI ANTIOKSIDAN

Wulandari, Monika Retno (2021) FORMULASI SEDIAAN SERUM EKSTRAK ETANOL DAUN UBI JALAR UNGU (Ipomoea batatas (L.) Lamk) SEBAGAI ANTIOKSIDAN. Skripsi thesis, Universitas Setia Budi.

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Abstract

Purple sweet potato leaves (Ipomoea batatas (L.) Lamk) are the type of plant that contains flavonoids, saponins, polyphenols, and tannins. The results of phytochemical screening showed that purple sweet potato leaves had antioxidant activity. The purpose of this study are to determine physical quality, stability, and antioxidant activity of serum formulated with various concentrations of purple sweet potato leaves ethanol extract. Purple sweet potato leaf extract obtained from maceration with 70% ethanol. Serum is a preparation with high concentrations of active substances and low viscosity, because of that the effect is absorbed more quickly and spreads easily on the skin. serum preparation was made by 5 formulas, formula 1 as negative control, formula 2,3,4 with variations in the contentration of extract contained 0.5%, 1%, 2%, and formula 5 as positive control. Serum preparations tested for physical quality include organoleptic test, homogeneity test, pH test, spreadability test, viscosity test, and stability test. Antioxidant activity testing used the DPPH method. The results showed that all serum formulations had a good physical quality test. The results of the antioxidant activity test for serum preparations in formulas 1, 2, 3, 4, and 5 with IC50 values = 384,083 ppm, 55,0689 ppm, 49,1636 ppm, 39,9459 ppm, and 31,8174 ppm. Formula 4 with an extract concentration of 2% has the strongest antioxidant activity with a value of IC50= 39,9459 ppm. Key words: Purple sweet potato leaf extract, antioxidants, serum

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Purple sweet potato leaf extract, antioxidants, serum
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	13 Jun 2022 06:54
Last Modified:	13 Jun 2022 06:54
URI:	http://repo.setiabudi.ac.id/id/eprint/4852

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