EFEKTIVITAS EKSTRAK DAUN TURI (Sesbania grandiflora Pers.) TERHADAP PERTUMBUHAN Candida albicans ATCC 10231 PADA PLAT RESIN AKRILIK

Jayanti, Saras Dwi (2020) EFEKTIVITAS EKSTRAK DAUN TURI (Sesbania grandiflora Pers.) TERHADAP PERTUMBUHAN Candida albicans ATCC 10231 PADA PLAT RESIN AKRILIK. Skripsi thesis, Universitas Setia Budi.

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Abstract

The use of dentures if they do not maintain proper oral hygiene can be a place for attachment of food debris which can increase the number of microorganisms in the oral cavity, one of which is the fungus Candida albicans. One of the natural disinfectants is plant turi (Sesbania grandiflora Pers.). Turi leaves contain saponins, flavonoids and tannins which are reported to have antifungal effects. The purpose of this study was to determine the MIC value and the effective concentration of turi leaf extract which has antifungal activity in inhibiting the growth of Candida albicans ATCC 10231 on acrylic resin plates. The simplicia of turi leaves was macerated with 70% ethanol as solvent. The extraction results were then carried out by phytochemical tests, TLC tests and antifungal activity. Acrylic resin plate samples with a size (10x10x1) mm of 15 were divided into 5 immersion groups, namely the 12,5%, 25% and 50% turi leaf extract concentration group, the negative control group (sterile distilled water) and a positive control (chlorhexidine gluconate 0,2%). The results of statistical calculations using the One-Way ANOVA test and followed by the Post Hoc LSD test to see which treatments have significant differences between groups. Phytochemical results obtained by saponins, tannins, flavonoids, alkaloids, steroids, and terpenoids. The results showed that the MIC value was at a concentration of 12,5%, and a concentration of 50% which was the most effective in inhibiting the growth of Candida albicans fungi on acrylic resin plates. Keywords: Acrylic resin, Candida albicans, turi leaf extract.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Acrylic resin, Candida albicans, turi leaf extract.
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	16 Jun 2022 07:20
Last Modified:	16 Jun 2022 07:20
URI:	http://repo.setiabudi.ac.id/id/eprint/4873

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