Septianasari, Adellya (2021) PENGARUH VARIASI KONSENTRASI GELLING AGENT TERHADAP MUTU FISIK DAN AKTIVITAS GEL ANTIOKSIDAN EKSTRAK DAUN MURBEI (Morus alba L.) DENGAN METODE DPPH. Skripsi thesis, Universitas Setia Budi.
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Abstract
Mulberry (Morus alba L.) is plant that is widely used as medicine. The active compounds that found in mulberry leaves are alkaloid, flavonoids, polyphenols and terpenoids which have an activity as antioxidants. This study aums to determine the effect of a combination of HPMC E4M and carbopol 940 as a gelling agent in mulberry leaf extract gel (Morus alba L.) to determine the proportion value of HPMC E4M and carbopol 940 which can produce mulberry leaf extract gel formulation (Morus alba L.) The gel was made in a concentration 2.5% of mulverry leaf extract in formulas 1,2 ad 3 with a concentration of HPMC E4M and carbopol 940 F1 (1.5%:0.5%), F2 (1%:1%), and F3 (0.5%:1.5%). The physical quality properties of the gel were tested for homogeneity, organolepticism, viscosity, disperbility, adhesion, pH test, stability and tested for their antioxidant activity in each formula. The data obtained were analyzed by one way ANOVA at a 95% confidence level. The result showed that the ethanol extract of mulberry leaves can be made a good gel preparation with a combination of gelling agent HPMC E4M and Carbopol 940 by testing the physical quality of the gel and its stability with best formula result in formula 1. The results of the antioxidant test were carried out by the DPPH method with the calculation of the IC50 value, the best result were obtained in formula 2 with an IC50 value 73.26 ppm, including the strong category. Key words : Mulberry leaf extract, HPMC E4M, Carbopol 940, Antioxidant, IC50
| Item Type: | Thesis (Skripsi) |
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| Uncontrolled Keywords: | Mulberry leaf extract, HPMC E4M, Carbopol 940, Antioxidant, IC50 |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
| Depositing User: | Tifany Nur Arfiana |
| Date Deposited: | 21 Jul 2022 03:57 |
| Last Modified: | 21 Jul 2022 03:57 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/4923 |
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