EVALUASI INTERAKSI OBAT PADA PASIEN PNEUMONIA GERIATRI DI INSTALASI RAWAT INAP RSUD Dr. R. SOEDJATI SOEMODIARDJO PURWODADI TAHUN 2019

Anggraeni, Alifia Rahma (2021) EVALUASI INTERAKSI OBAT PADA PASIEN PNEUMONIA GERIATRI DI INSTALASI RAWAT INAP RSUD Dr. R. SOEDJATI SOEMODIARDJO PURWODADI TAHUN 2019. Skripsi thesis, Universitas Setia Budi.

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Abstract

In geriatrics, pneumonia is among the top five causes of death. Pneumonia in geriatrics most them are asymptomatic. Pneumonia therapy is given antibiotics and supportive therapy. Polypharmacy can increase the occurrence of drug interactions. Drug interactions can be prevented and minimized by monitoring. The purpose of this study was to determine the potential of drug interactions, the mechanism of interactions, and the severity of interactions in the medication of geriatric pneumonia patients. This research uses a retrospective design with purposive sampling of drug use data of geriatric pneumonia patients who were hospitalized in 2019 at Dr. R. Soedjati Soemodiardjo Purwodadi Hospital. Medical record data were used to evaluate drug interactions in the treatment of geriatric pneumonia patients. Drug use data were analyzed with Medscape and Lexicomp Drug Interaction Checker identified based on mechanism and the severity level. The results showed that drug interactions were found in 92 patients (60.53%) with a total incidence of 208 incidences. The most common interaction was lansoprazole with aminophylline and digoxin with furosemide as many as 20 events (9.62%). The most common mechanism of interaction was pharmacodynamic interactions which were 139 cases (66.83%), the most severe level of the interactions was minor 112 interactions (53.85%). Keywords: drug interactions, geriatric, pneumonia.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	drug interactions, geriatric, pneumonia.
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	21 Jul 2022 03:57
Last Modified:	21 Jul 2022 03:57
URI:	http://repo.setiabudi.ac.id/id/eprint/4931

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