FORMULASI SEDIAAN GEL LENDIR BEKICOT (Achatina fulica) DENGAN VARIASI KONSENTRASI KARBOPOL TERHADAP LUKA SAYAT (Vulnus scissum) PADA PUNGGUNG KELINCI New Zealand

Audyna, Nanda Sawiya (2021) FORMULASI SEDIAAN GEL LENDIR BEKICOT (Achatina fulica) DENGAN VARIASI KONSENTRASI KARBOPOL TERHADAP LUKA SAYAT (Vulnus scissum) PADA PUNGGUNG KELINCI New Zealand. Skripsi thesis, Universitas Setia Budi.

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Abstract

Snail slime contains achasin isolate as an antibacterial and heparin sulfate which affects the increase in fibroblasts as an extracellular matrix that will accelerate wound healing. This study aims to determine snail slime which is formulated into a gel preparation with good physical properties and stability, the effect of variations in carbopol concentrations and its effectiveness in accelerating the healing of wound. Snail slime was centrifuged for separation from its feces and formulated into gel preparations with variations in carbopol concentrastions of 1%, 1.5%, and 2%, then tested the physical quality and stability of the preparation using the Cycling test method. The gel formula was tested for wound healing activity on the back of New Zealand rabbits. The results showed that the snail slime gel preparation had good physical properties and stability during storage. The increase in the concentration of carbopol causes the viscocity and adhesion to increase, while the pH and dispersion decreased. Carbopol also affects the activity of wound healing. The most effective formula in the wound healing process is Formula 1 with 1% carbopol concentration. Key word : snail slime (Achatina fulica), incision wound (Vulnus scissum), gel

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	snail slime (Achatina fulica), incision wound (Vulnus scissum), gel
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	29 Jul 2022 07:46
Last Modified:	29 Jul 2022 07:46
URI:	http://repo.setiabudi.ac.id/id/eprint/5013

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