UJI AKTIVITAS ANTIJAMUR SEDIAAN MOUTHWASH EKSTRAK BUNGA CENGKEH (Syzygium aromaticum L) TERHADAP Candida albicans

Rini, Arneta Adityo (2022) UJI AKTIVITAS ANTIJAMUR SEDIAAN MOUTHWASH EKSTRAK BUNGA CENGKEH (Syzygium aromaticum L) TERHADAP Candida albicans. Skripsi thesis, Universitas Setia Budi.

	Text ABSTRAK.pdf Download (12kB)
	Text BAB I.pdf Download (962kB)
	Text BAB II.pdf Restricted to Repository staff only Download (298kB) | Request a copy
	Text BAB III.pdf Restricted to Repository staff only Download (205kB) | Request a copy
	Text BAB IV.pdf Restricted to Repository staff only Download (447kB) | Request a copy
	Text BAB V.pdf Restricted to Repository staff only Download (7kB) | Request a copy
	Text DAFTAR PUSTAKA.pdf Download (258kB)
	Text LAMPIRAN.pdf Download (1MB)
	Text Form pernyataan publikasi-ARNETA ADITYORINI-24185374A.pdf Download (269kB)
	Text Surat Keterangan Bebas Plagiasi.pdf Download (30kB)

Abstract

Candida albicans infects the oral cavity with characteristic white patches when scraped off leaving a red and bloody surface on the gingiva, tongue, and mucous membranes called candidiasis. Clove flower has antifungal activity. Humectant (glycerol) serves to reduce evaporation and prolong contact with teeth in mouthwash. This study aims to formulate a mouthwash with varying concentrations of glycerol from clove flower extract which has antifungal activity against Candida albicans. The extract was obtained by maceration using 96% ethanol. The mouthwash formulation was made with three variations of extract concentration 5; 7.5; 15% was used which was the most effective and used variations in the concentration of glycerol 10; 15; 20%. The positive control used 0.2% chlorhexidine gluconate and the negative control was a mouthwash formula without extract. PHysical quality testing includes organoleptic test, pH, viscosity, stability. The antifungal activity was tested using the disc diffusion method. The data was processed using Shapiro-Wilks statistics followed by One Way ANOVA. The results of the antifungal activity of clove flower extract concentration 5; 7.5; 10% resulted in inhibition zones of 14.92mm±0.71; 16.08mm±0.11; 19.00mm±0.35. Mouthwash preparations with variations in concentration of 15% glycerol base have good pHysical quality. Clove flower extract mouthwash preparation with 10% concentration with variation of glycerol 10; 15; 20% resulted in an inhibition zone of 14.16mm±0.11 respectively; 14.83mm±0.51; 13.58mm±0.23 with a positive control of 20.91mm±0.7169 (p<0.05) but the antifungal activity of the extract was still included in the strong category. Key words : Syzygium aromaticum L, mouthwash, glycerol, Candida albicans

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Syzygium aromaticum L, mouthwash, glycerol, Candida albicans
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	29 Sep 2022 04:38
Last Modified:	29 Sep 2022 04:38
URI:	http://repo.setiabudi.ac.id/id/eprint/5259

Actions (login required)

View Item