UJI MUTU FISIK MASKER GEL PEEL-OFF LENDIR BEKICOT (Achatina fulica) DAN UJI AKTIVITAS ANTIBAKTERI TERHADAP BAKTERI Staphylococcus epidermidis ATCC 12228

Candra, Fiefie Faprelia Ayudea (2022) UJI MUTU FISIK MASKER GEL PEEL-OFF LENDIR BEKICOT (Achatina fulica) DAN UJI AKTIVITAS ANTIBAKTERI TERHADAP BAKTERI Staphylococcus epidermidis ATCC 12228. Skripsi thesis, Universitas Setia Budi.

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Abstract

Snails (Achatina fulica) contain mucus and are often considered disgusting. Snail slime was found to contain large amounts of Achasin protein which has an antibacterial effect. The antibacterial was able to inhibit the acne-causing bacteria Staphylococcus epidermidis at a concentration of 10%. The purpose of this study was to determine whether the snail mucus peel-off gel mask preparation could meet the requirements for good physical quality and stability and have antibacterial activity against Staphylococcus epidermidis bacteria by observing the inhibition zone formed. The research was carried out experimentally, samples of snail mucus (Achatina fulica) were formulated into a peel-off gel mask preparation with three concentration variations, namely F1 15%, F2 25%, and F3 35%. Then the physical quality and stability tests were carried out. The three formulas were tested for antibacterial activity using the well diffusion method. The data from the physical quality test and the test of the bacterial inhibition zone formed were analyzed by SPSS (Statistical Package for the Social Sciences). . Evaluation of the physical quality of the peel-off gel mask preparation was carried out on several parameters such as organoleptic, homogeneity, pH, viscosity, dispersion, drying time, and accelerated stability using the cycling test method. The results showed that formulas 1,2 and 3 had good physical quality and stability. The three formulas were tested for antibacterial activity with the results of the inhibition in formula 1 being 11.51 mm, formula 2 being 14.27 mm, and formula 3 being 17.45 mm. The results showed that formula 3 had the most effective inhibition and was classified as an antibacterial with a medium category. Keywords : Snail mucus, Peel-off gel mask, Antibacterial, Staphylococcus epidermidis

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Snail mucus, Peel-off gel mask, Antibacterial, Staphylococcus epidermidis
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	10 Oct 2022 07:29
Last Modified:	10 Oct 2022 07:29
URI:	http://repo.setiabudi.ac.id/id/eprint/5307

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