UJI AKTIVITAS ANTIPLATELET EKSTRAK ETANOL RIMPANG JAHE EMPRIT (Zingiber officinale var Amarum) PADA MENCIT PUTIH (Mus musculus L.)

Yulianingrum, Krisma Riski (2022) UJI AKTIVITAS ANTIPLATELET EKSTRAK ETANOL RIMPANG JAHE EMPRIT (Zingiber officinale var Amarum) PADA MENCIT PUTIH (Mus musculus L.). Skripsi thesis, Universitas Setia Budi.

	Text 1. ABSTRAK (1).pdf Download (191kB)
	Text 4. BAB I (1).pdf Download (822kB)
	Text 5. BAB II (1).pdf Restricted to Repository staff only Download (387kB) | Request a copy
	Text 6. BAB III (1).pdf Restricted to Repository staff only Download (455kB) | Request a copy
	Text 7. BAB IV (1).pdf Restricted to Repository staff only Download (343kB) | Request a copy
	Text 8. BAB V (1).pdf Restricted to Repository staff only Download (185kB) | Request a copy
	Text 9. DAFTAR PUSTAKA (1).pdf Download (315kB)
	Text 10. LAMPIRAN (1).pdf Download (1MB)
	Text 2. FORM PERNYATAAN PUBLIKASI (1).pdf Download (46kB)
	Text 3. SURAT KETERANGAN BEBAS PLAGIASI.pdf Download (29kB)

Abstract

Platelets are blood cells that play a role in the hemostatic process. Platelets aggregate to form a hemostatic plug when an injury occurs. Antiplatelet pharmacological therapy known in the market is aspirin. The purpose of this study was to determine whether the ethanol extract of emprit ginger rhizome (Zingiber officinale var Amarum) had antiplatelet activity and to determine the effective dose of emprit ginger rhizome ethanol extract (Zingiber officinale var Amarum) as antiplatelet. The study used 25 mice divided into 5 groups and each group contained 5 mice. Group I positive control was given aspirin; group II negative control was given 0.5% CMC Na; the extract dose group was 4.1 mg/20 g BB; extract dose group 8.2 mg/20 g BB; the extract dose group was 12.3 mg/20 g BB. The treatment was carried out for 9 days then measurements were made on day 0 (T0) and day 9 (T1). The data will be tested with a paired T-test to determine the difference before and after administration of the test preparation and the one way ANOVA test on the percent increase and decrease in each group. The results showed that the ethanol extract of emprit ginger rhizome (Zingiber officinale var Amarum) had antiplatelet activity. The effective dose of ethanol extract of emprit ginger rhizome (Zingiber officinale var Amarum) which has antiplatelet activity is 8.2 mg/20 g BB. Keyword : Ginger emprit, Zingiber officinale var Amarum, Antiplatelet.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Ginger emprit, Zingiber officinale var Amarum, Antiplatelet.
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	10 Oct 2022 07:30
Last Modified:	10 Oct 2022 07:30
URI:	http://repo.setiabudi.ac.id/id/eprint/5342

Actions (login required)

View Item