FORMULASI EMULGEL EKSTRAK DAUN PEGAGAN (Centella asiatica (L.) Urban) DAN UJI AKTIVITAS ANTIBAKTERI TERHADAP Staphylococcus aureus ATCC 25923

Rini, Desi Puspita (2022) FORMULASI EMULGEL EKSTRAK DAUN PEGAGAN (Centella asiatica (L.) Urban) DAN UJI AKTIVITAS ANTIBAKTERI TERHADAP Staphylococcus aureus ATCC 25923. Skripsi thesis, Universitas Setia Budi.

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Abstract

Centella asiatica leaf extract has antibacterial activity against Staphylococcus aureus ATCC25923. Centella asiatica leaf extract is formulated into the form of emulgel. This study aims to determine the effect of variations in the concentration of carbopol 940 on antibacterial activity on Staphylococcus aureus ATCC 25923 and the physical properties of emulgel preparations. This study used six formulas with a carbopol content of 940 0.5%, 1.5% and 2% plus three negative controls. The physical properties of emulgel were tested for organolepticity, dispersal power, adhesion, viscosity, pH and stability. Antibacterial testing using the welling method. The pouring media on the saucer was then smeared with the well method and added to each variation in carbopol concentration, positive control and negative control. Test results The physical properties of emulgel and measurement of infection diameter were analyzed using Saphiro-Wilk. The results showed that variations in the concentration of carbopol 940 affected the physical properties and inhibitory power values of Staphylococcus aureus ATCC 25923. The emulgel formula of Centella asiatica leaf extract with a carbopol concentration of 1.5% meets good physical properties and has good inhibitory power compared to carbopol 940 concentrations of 0.5% and 2%. Kata kunci : Antibacterial, Staphylococcus aureus ATCC 25923, Extract, Centella asiatica (L.)Urban) ATCC 25923, Emulgel.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Antibacterial, Staphylococcus aureus ATCC 25923, Extract, Centella asiatica (L.)Urban) ATCC 25923, Emulgel.
Subjects:	R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	30 Nov 2022 02:59
Last Modified:	30 Nov 2022 02:59
URI:	http://repo.setiabudi.ac.id/id/eprint/5477

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