FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN EMULGEL ANTIJERAWAT MINYAK ATSIRI KULIT BATANG KAYU MANIS (Cinnamomum burmanii) TERHADAP BAKTERI Staphylococcus aureus

Yulianti, Elsa (2022) FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN EMULGEL ANTIJERAWAT MINYAK ATSIRI KULIT BATANG KAYU MANIS (Cinnamomum burmanii) TERHADAP BAKTERI Staphylococcus aureus. Skripsi thesis, Universitas Setia Budi.

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Abstract

Acne is a skin disease that is often experienced by teenagers during puberty. Active glands that are buried and clogged due to dirt can trigger infection due to contamination with Staphylococcus aureus. Cinnamon bark has antibacterial activity because the compounds contained in it are eugenol and cinnamaldehyde compounds which can inhibit the growth activity of Staphylococcus aureus. Cinnamon bark essential oil of 1% was made into an emulgel preparation with a concentration of 2% HPMC; 2.5% ; 3%. Emulgel preparations were tested for organoleptic, pH, adhesion, spreadability, homogeneity, viscosity and stability and antibacterial activity test using the well method. The results of the data continued with statistical analysis testing using SPSS with Paired T-test. The results showed that cinnamon bark essential oil emulgel preparations with base concentrations of 2%, 2.5%, and 3% had good physical quality and unstable stability. Base concentration affects the stability of the preparation. The higher the concentration of the base the better the resulting stability. The results of the antibacterial activity test with 1% cinnamon bark essential oil obtained a strong inhibition zone on the emulgel where F4, F5 and F6 obtained inhibition zones of 19.67 mm, 19.5 mm, and 20.33 mm. Formulation 1, 2, and 3 did not produce inhibition zones formed. Keywords: Staphylococcus aureus, Cinnamomum burmanii, emulgel, Antibacterial

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Staphylococcus aureus, Cinnamomum burmanii, emulgel, Antibacterial
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	30 Nov 2022 02:57
Last Modified:	30 Nov 2022 02:57
URI:	http://repo.setiabudi.ac.id/id/eprint/5492

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