UJI EFEKTIVITAS GEL EKSTRAK DAUN INSULIN (Tithonia diversifolia Gray) SEBAGAI PENYEMBUH LUKA BAKAR PADA PUNGGUNG KELINCI New Zealand

Safitri, Indri (2022) UJI EFEKTIVITAS GEL EKSTRAK DAUN INSULIN (Tithonia diversifolia Gray) SEBAGAI PENYEMBUH LUKA BAKAR PADA PUNGGUNG KELINCI New Zealand. Skripsi thesis, Universitas Setia Budi.

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Abstract

A condition known as burns occurs when the skin is exposed to a heat source, burns can harm the skin epidermis as well as tissues triggering an inflammatory response that can have systemic and local pathophysiological effects. Mexican Sunflower (Tithonia diversifolia Gray) includes plants containing flavonoids, saponins, and tannins. Saponins are also able to support the epithelialization process and stimulate the formation of new epithelial cells that can reduce the diameter of the wound. The aim of the study was to determine whether the Mexican sunflower leaf extract gel was successful in curing second degree burns on the backs of New Zealand rabbits and to determine whether the quality and physical stability of the gel were satisfactory. The method of making shallow second-degree burns uses the Akhoondinasab method. The maceration process is followed by remaceration which is used to make Mexican sunflower leaf extract. The manufacture of Mexican sunflower leaf extract gel was divided into 3 concentrations with the basic variation of carbopol. The insulin leaf gel was tested for its burn healing activity and its physical qualities including organoleptic, dispersibility, pH, homogeneity and viscosity. Two way Anova is used to check the percentage of findings using parametric statistics ANOVA (Analysis of Variance) The results obtained in the study were that the insulin leaf extract gel formulation with a variation of the concentration of 3% carbopol additive in formula 1 had the most effective wound healing activity compared to other formulas. Keywords: Burns, Mexican sunflower leaf (Tithonia diversipholia Gray), New Zealand rabbits, gel

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Burns, Mexican sunflower leaf (Tithonia diversipholia Gray), New Zealand rabbits, gel
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	30 Nov 2022 04:19
Last Modified:	30 Nov 2022 04:19
URI:	http://repo.setiabudi.ac.id/id/eprint/5521

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