UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAN FRAKSI RIMPANG ALANG-ALANG (Imperata cylindrica L) SERTA BIOAUTOGRAFI FRAKSI TERAKTIF TERHADAP BAKTERI Escherichia coli ATCC 25922

ALWAZIRUL, MAHDI (2022) UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAN FRAKSI RIMPANG ALANG-ALANG (Imperata cylindrica L) SERTA BIOAUTOGRAFI FRAKSI TERAKTIF TERHADAP BAKTERI Escherichia coli ATCC 25922. Skripsi thesis, Universitas Setia Budi.

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Abstract

Escherichia coli is the most common bacterium that causes diarrhea, especially in children. Alang-alang has been used as a traditional medicine for internal heat, and as a urine stream. This study aims to determine the antibacterial activity of the extract and fraction of alang-alang rhizome, the most active activity of the extract and fraction, and the class of compounds contained in the most active fraction of the rhizome of alang-alang. The extraction method used in this research is 70% ethanol maceration method, fraction, and well diffusion. The test concentrations used were 10%, 15%, 20%, positive control of ciprofloxacin antibiotic, and 1% negative control of DMSO. The diffusion method was carried out by measuring the diameter of the inhibition zone around the well. The results showed a concentration of 20% in the extract, nhexane, ethyl acetate, and water fractions. Each gave an inhibition zone diameter of 15.166 mm, 7.833 mm, 12.2 mm, 11.2 mm on Escherichia coli ATCC 25922. The extract and the ethyl acetate fraction were the most effective, then bioautography was performed on Escherichia coli bacteria, the results showed the fraction Ethyl acetate contains flavonoid compounds. Key words: Escherichia coli, diarrhea, Imperata root, extract, fraction, bioautography.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Escherichia coli, diarrhea, Imperata root, extract, fraction, bioautography.
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	30 Nov 2022 04:17
Last Modified:	30 Nov 2022 04:17
URI:	http://repo.setiabudi.ac.id/id/eprint/5535

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