LITERATURE REVIEW: AKTIVITAS ANTIDIABETES BIJI MAHONI (Swietenia mahagoni Jacq.)

Rahayu, Rohmah Tri (2022) LITERATURE REVIEW: AKTIVITAS ANTIDIABETES BIJI MAHONI (Swietenia mahagoni Jacq.). Skripsi thesis, Universitas Setia Budi.

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Abstract

Diabetes mellitus is a chronic disease whose prevalence is always increasing. Mahogany seeds (Swietenia mahagoni Jacq.) contain saponin compounds and flavonoids that function to lower blood glucose levels. The purpose of this study was to determine the antidiabetic activity, compound content, and find out the mechanism of antidiabate activity in mahogany seeds based on literature review. This research was conducted using the literature review method to determine the activity of antidiabetics, the content of compounds in mahogany seeds (Switenenia mahagoni Jacq.) and their mechanism of action. Literature review using a journal database on Google Scholar and Science Direct. A total of 17 journals met the inclusion criteria. The information is then analyzed and interpreted and then conclusions are drawn. The results of antidiabetic studies on mahogany seeds (Swietenia mahagoni Jacq.) have antidiabetic activity with parameters of decreasing blood sugar levels, increasing the percentage of inhibition of -glucosidase, improvement of pancreatic organs, weight, SOD activity, decreased HbA1C levels, as well as a decrease in DM complications with compounds containing flavonoids, limonoids, alkaloids and phenols. The mechanism of antidiabetic activity by becoming a natural agonist of PPARγ, increasing insulin sensitivity, regenerating damaged cells β pancreas and reducing insulin resistance. Keyword : Mahagoni seed (Swietenia mahagoni Jacq.), Literature Review, Antidiabetic activity

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Mahagoni seed (Swietenia mahagoni Jacq.), Literature Review, Antidiabetic activity
Subjects:	R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	30 Nov 2022 03:06
Last Modified:	30 Nov 2022 03:06
URI:	http://repo.setiabudi.ac.id/id/eprint/5608

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