UJI AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK DAUN PEPAYA (Carica papaya) DAN DAUN KOPASANDA (Chromolaena odorata) TERHADAP BAKTERI Staphylococcus aureus

Rohmaniah, Rohmaniah (2022) UJI AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK DAUN PEPAYA (Carica papaya) DAN DAUN KOPASANDA (Chromolaena odorata) TERHADAP BAKTERI Staphylococcus aureus. Skripsi thesis, Universitas Setia Budi.

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Abstract

Pepaya leaves (Carica papaya) and leaves kopasanda (Chromolaena odorata) have antibacterial activity of staphylococci aureus. Both have the tannin compounds, flavonoid, alkaloid, terpenoid, saponin, steroid, and phenol. This study attempts to test combination extract antibacterial activity leaves pepaya (carica papaya) and leaves kopasanda (Chromolaena odorata) of against bacteria of Staphylococcus aureus. Pepaya leaves and leaves in the extraction kopasanda use of maceration using a solvent ethanol 70 % followed concentrated. Testing methods have antibacterial activity dilution to set a value kill concentration as high as this and learning process that is used as the determination of the concentration of the combination of best who do again their activities as an antibacterial. To establish a method of diffusion diameter obstruent. teraktif as a combination ofThen used the combination use discs. Dilution method use single out extract pepaya leaves and leaves kopasanda with konsetrasi 50 %, 25 %, % 12,5, % 6,25, 3,125, % 1,56, % 0,78, 0,39 % . The results of the dilution method test with the results of KBM from pepaya leaf extract with a concentration of 12.5% and kopasanda leaf extract with a concentration of 25% were able to kill bacterial growth. The diffusion test used a combination dose of pepaya leaf extract and kopasanda leaf extract with a ratio of (1:1), (2:1), and (1:2). The results of the test using a combination (2:1) showed the greatest inhibitory activity against S. aureus bacteria with an average inhibitory diameter of 20.10 mm. The results of the combination interaction pattern test using the most active combination (2:1) obtained synergistic. Keywords: Combination, antibacterial, Pepaya leaves (Carica papaya), Kopasanda leaves(Chromolaena odorata), Staphylococcus aureus

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Kopasanda leaves(Chromolaena odorata), Staphylococcus aureus
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	30 Nov 2022 04:18
Last Modified:	30 Nov 2022 04:18
URI:	http://repo.setiabudi.ac.id/id/eprint/5609

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