EFEK KOMBINASI EKSTRAK ETANOL DAUN BELIMBING WULUH (Averrhoa bilimbi L.) DAN DAUN PEPAYA (Carica papaya L.) TERHADAP BAKTERI Staphylococcus aureus ATCC 25923 DENGAN METODE PITA KERTAS

RAHMANSYAH, ROSANNO ADHI PRAMANA (2022) EFEK KOMBINASI EKSTRAK ETANOL DAUN BELIMBING WULUH (Averrhoa bilimbi L.) DAN DAUN PEPAYA (Carica papaya L.) TERHADAP BAKTERI Staphylococcus aureus ATCC 25923 DENGAN METODE PITA KERTAS. Skripsi thesis, Universitas Setia Budi.

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Abstract

Infectious diseases are the second leading cause of death after cardiovascular disease. One of the microbes that causes infection is Staphylococcus aureus. Bacterial resistance to antibiotics causes the death rate to increase. Belimbing wuluh leaves and papaya leaves contain active compounds of flavonoids, saponins, tannins and alkaloids that have the potential as antibacterial of Staphylococcus aureus. This study aims to determine the activity of the combination of ethanol extract of star fruit and papaya leaves against Staphylococcus aureus ATCC 25923. Wuluh starfruit leaves and papaya leaves were extracted by maceration method using 96% ethanol solvent and then identified the group of compounds. The combination of starfruit leaf extract and papaya leaf extract at an extract concentration of 20% made variations in the concentration ratio (1:1), (1:2) and (2:1). Testing of antibacterial activity against Staphylococcus aureus bacteria using the disc diffusion method and determining the effect of the combination using the paper tape method. The data were analyzed statistically with the Shapiro-Wilk test followed by the one way ANOVA, Kruskal Wallis and Mann Whitney tests. The results showed that the combination of ethanol extract of star fruit and papaya leaves had antibacterial activity against Staphylococcus aureus ATCC 25923. The most effective combination of extracts was shown in a concentration ratio of 2:1 with average inhibition zone diameter of 18 mm ± 0.2 mm and give the effect synergistic combination against Staphylococcus aureus ATCC 25923. Keywords : Antibacterial, Wuluh Starfruit Leaf, Papaya leaf, Staphylococcus aureus

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Antibacterial, Wuluh Starfruit Leaf, Papaya leaf, Staphylococcus aureus
Subjects:	R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	30 Nov 2022 02:48
Last Modified:	30 Nov 2022 02:48
URI:	http://repo.setiabudi.ac.id/id/eprint/5611

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