AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK ETANOL DAUN JARAK PAGAR (Jatropha curcas L.) DAN DAUN SIRIH (Piper betle L.) TERHADAP Staphylococcus aureus ATCC 25923

Lestari, Titik Puji (2022) AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK ETANOL DAUN JARAK PAGAR (Jatropha curcas L.) DAN DAUN SIRIH (Piper betle L.) TERHADAP Staphylococcus aureus ATCC 25923. Skripsi thesis, Universitas Setia Budi.

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Abstract

Staphylococcus aureus is one of the main cause of nosocomial infections in various countries, this bacteria has been resistant to various kinds of antibacterials. Jatropha (Jatropha curcas L.) and betel (Piper betle L.) plants contain tannins, saponins, flavonoids, alkaloids, and essential oils that can be used as antibacterial. This study aims to determine the most effective antibacterial activity of the combination of jatropha leaf extract and betel leaf against Staphylococcus aureus bacteria, and to determine the effect of the combination. Jatropha leaf extract and betel leaf extract were made by maceration using 96% ethanol as a solvent. The combination of jatropha leaf extract and betel leaf extract with each extract concentration of 20% made variations in concentration at (1:1), (1:2), and (2:1). The antibacterial activity test method used the disc diffusion method, while the combined effect was determined using the paper tape method. The results showed that the combination of fencing castor leaf ethanol extract and betel leaf had antibacterial activity against Staphylococcus aureus ATCC 25923. The combination concentration of 1:2 is the most effective combination with an average diameter of 20,35 ± 0,31 mm and provides a synergistic combination effect on Staphylococcus aureus ATCC 25923. Keyword: Staphylococcus aureus, antibacterial, Jatropha leaf, betel leaf.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Staphylococcus aureus, antibacterial, Jatropha leaf, betel leaf.
Subjects:	R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	30 Nov 2022 02:45
Last Modified:	30 Nov 2022 02:45
URI:	http://repo.setiabudi.ac.id/id/eprint/5634

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