UJI AKTIVITAS KRIM ANTI-AGING EKSTRAK ETANOL DAUN MUDA PEPAYA (Carica Papaya L.) PADA KULIT PUNGGUNG KELINCI NEW ZEALAND YANG DIPAPAR SINAR UV-A

Permatasari, Devi Intan (2023) UJI AKTIVITAS KRIM ANTI-AGING EKSTRAK ETANOL DAUN MUDA PEPAYA (Carica Papaya L.) PADA KULIT PUNGGUNG KELINCI NEW ZEALAND YANG DIPAPAR SINAR UV-A. Skripsi thesis, Universitas Setia Budi.

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Abstract

Aging causes the skin to become wrinkled. The cause of aging is free radicals, free radicals in the form of UV-A rays. Young papaya leaves (Carica papaya L.) as a source of antioxidants capable of providing anti-aging activity. This study was conducted to determine the activity of cream of ethanol extract of papaya young leaves as anti-aging using rabbits exposed to UV-A light. Young papaya leaf extract (Carica papaya L.) was tested for drying shrinkage and chemical content identification. Cream preparations were made using young papaya leaf extract followed by testing the physical quality of the cream. Anti-aging activity test using 5 New Zealand rabbits. Rabbits that had been shaved were induced using UV-A light for 6 hours a day for 2 weeks. The skin of the rabbit's back was smeared with negatif control, positive control, and cream of 2.5%, 5% and 10% ethanol extract of young papaya leaves for 30 days. Observation of the parameters of percent collagen, percent elasticity, and moisture percent were carried out before induction, after induction and after the rabbit's back was smeared with cream using a skin analyzer. The results of testing the physical quality of F1, F2, F3 and F4 cream fulfilled the organoleptic requirements, homogeneity, viscosity, pH, stickiness, spreadability and protection power. For the safety test of the cream, the cream is very slightly irritating. In the anti-aging activity test, young papaya leaf extract with a concentration of 5% gave the best anti-aging effect. Keywords: papaya leaf extract, anti-aging activity, cream, UV-A rays, skin analyzer.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	papaya leaf extract, anti-aging activity, cream, UV-A rays, skin analyzer.
Subjects:	R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	05 Apr 2023 02:56
Last Modified:	05 Apr 2023 02:56
URI:	http://repo.setiabudi.ac.id/id/eprint/5766

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