Swary, Ines Nabila (2023) UJI EFEKTIVITAS EKSTRAK KULIT KENTANG (Solanum tuberosum L.) TERHADAP PENURUNAN KADAR GULA DARAH DAN GAMBARAN HISTOPATOLOGI PANKREAS PADA MENCIT (Mus musculus L.) YANG DIINDUKSI ALOKSAN. Skripsi thesis, Universitas Setia Budi.
![[img]](http://repo.setiabudi.ac.id/style/images/fileicons/text.png) |
Text
ABSTRAK.pdf Download (91kB) |
|
Text
BAB I.pdf Download (587kB) |
|
Text
BAB II.pdf Restricted to Repository staff only Download (512kB) | Request a copy |
|
Text
BAB III.pdf Restricted to Repository staff only Download (264kB) | Request a copy |
|
Text
BAB IV.pdf Restricted to Repository staff only Download (800kB) | Request a copy |
|
Text
BAB V.pdf Restricted to Repository staff only Download (6kB) | Request a copy |
|
Text
DAFTAR PUSTAKA.pdf Download (213kB) |
|
Text
LAMPIRAN.pdf Download (2MB) |
|
Text
form pernyataan publikasi iness.pdf Download (163kB) |
|
Text
INES SUKET 23 DES.pdf Download (22kB) |
Abstract
An increase in blood glucose levels characterizes hyperglycemia. Common symptoms that can be caused by diabetes include drinking a lot, frequent urination, decreased body weight, periodic drowsiness, and wounds that don't heal quickly. DM can be treated with traditional medicines, one of which is potato skins which contain chlorogenic acid, a class of flavonoids that can lower blood glucose levels by stimulating glucose uptake into the tissues. This study aims to determine the effect of ethanol extract from potato peel in reducing blood glucose levels in white mice and to determine the effective dose and its impact on the histopathological picture of the pancreas. This study used the maceration method with 70% ethanol solvent. Animals tested using 25 male white mice were divided into five groups, namely CMC 0.5%, glibenclamide, and ethanol extract of potato skins with three dose variations (dose 125, 250, and 500 mg/kg BW). The test animals were hyperglycemia induced by alloxan, and blood glucose levels were measured on days 0, 3, 10, and 17, and then the data were analyzed using the one-way ANOVA tes and continued with Post Hoc Tukey. The results showed that the ethanol extract of potato skins at doses of 125, 250, and 500 mg/kg BW could reduce blood sugar levels in mice and was able to regenerate the damaged pancreas. The effective dose in lowering blood sugar levels is a dose of 500 mg/kg bb. Keywords: potato skin, alloxan, hyperglycemia, pancreatic histopathology.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | potato skin, alloxan, hyperglycemia, pancreatic histopathology |
| Subjects: | R Medicine > RS Pharmacy and materia medica R Medicine > RV Botanic, Thomsonian, and eclectic medicine |
| Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
| Depositing User: | Tifany Nur Arfiana |
| Date Deposited: | 05 Apr 2023 02:54 |
| Last Modified: | 05 Apr 2023 02:54 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/5787 |
Actions (login required)
 |
View Item |
