Saputri, Niken Ayu (2023) UJI AKTIVITAS ANTIHIPERGLIKEMIA KOMBINASI EKSTRAK DAUN MANGGA KASTURI (Mangifera casturi) DAN DAUN SALAM (Syzygium polyanthum wight ) SERTA GAMBARAN ANALISIS HISTOPATOLOGI PANKREAS PADA MENCIT (Mus musculus L.) YANG DIINDUKSI ALOKSAN. Skripsi thesis, Universitas Setia Budi.
![[img]](http://repo.setiabudi.ac.id/style/images/fileicons/text.png) |
Text
ABSTRAK.pdf Download (407kB) |
|
Text
BAB I.pdf Download (991kB) |
|
Text
BAB II.pdf Restricted to Repository staff only Download (667kB) | Request a copy |
|
Text
BAB III.pdf Restricted to Repository staff only Download (450kB) | Request a copy |
|
Text
BAB IV.pdf Restricted to Repository staff only Download (891kB) | Request a copy |
|
Text
BAB V.pdf Restricted to Repository staff only Download (292kB) | Request a copy |
|
Text
DAPUS.pdf Download (326kB) |
|
Text
LAMPIRAN.pdf Download (4MB) |
|
Text
Form Publikasi.pdf Download (236kB) |
|
Text
niken suket 2 jan (1).pdf Download (23kB) |
Abstract
Kasturi mango leaves are known to contain mangiferin compounds and bay leaves contain quercitrin compounds which are responsible for antihyperglycemic activity. The aims of this study were to determine whether the combination of mango kasturi and bay leaf extracts could provide better antihyperglycemic activity than a single preparation, and to determine whether the combination of mango kasturi and bay leaf extracts could improve the histopathology of the pancreas of alloxan-induced mice. In this study, mango and bay leaves were extracted by maceration method with 96% ethanol solvent. The activity test was started by dividing the mice test animals into six groups, in one group consisting of five mice, namely the normal group, negative CMC Na 0.5%, positive for glibenclamide, single extract of mango kasturi leaf 150 mg/Kg BW, single leaf extract salam 250 mg/Kg BW, and a combination of mango kasturi leaf extract 75 mg/Kg BW and bay leaf extract 125 mg/Kg BW. Blood sugar levels were taken using a glucometer and data were analyzed with the help of SPSS (Statistical Product and Service Solutions). Pancreatic histopathological examination of mice with the Hematoxylin Eosin (HE) staining method. The results showed that the combination of mango kasturi and bay leaf extracts could provide better antihyperglycemic activity than a single preparation and could improve pancreatic histopathology (islet diameter of Langerhans) in alloxan-induced male white mice. Keywords : Alloxan, antihyperglycemic, glibenclamide, pancreatic histopathology.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | Alloxan, antihyperglycemic, glibenclamide, pancreatic histopathology. |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
| Depositing User: | Tifany Nur Arfiana |
| Date Deposited: | 05 Apr 2023 02:56 |
| Last Modified: | 05 Apr 2023 02:56 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/5808 |
Actions (login required)
 |
View Item |
