Hasanah, Finna Shoffiotul (2023) FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI MINYAK ATSIRI DAUN JERUK NIPIS (Citrus aurantyfolia, Swingle) DALAM SEDIAAN KRIM ANTI JERAWAT TERHADAP BAKTERI Staphylococus aureusa. Skripsi thesis, Universitas Setia Budi.
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Abstract
Lime leaf essential oil (Citrus auratyfolia, Swingle) contains limonene which is able to inhibit the growth of bacteria, namely the bacterium Staphylococuc aureus. Staphylococcus aureus is a grampositive bacteria which is one of the causes of acne formation. This study aims to determine the ability of lime leaf essential oil (Citrus auratyfolia, Swingle) in anti-acne cream preparations on Staphylococus aureus bacteria, determine the smallest concentration that can inhibit bacterial growth. Preparation of anti-acne cream from the essential oil of lime leaves (Citrus aurartfolia, Swingle) is made in a formula with a concentration of 10% on a stearic acid basis of 10 g, 15 g, 20 g. Cream is included in water-in-oil (A/M) or oil-in-water (O/A) preparations. Evaluation in the manufacture of the cream includes examination of organoleptic tests (smell, color, shape, and homogeneity), spreadability test, stickiness test, viscosity, pH. then finally evaluation of antibacterial activity. Antibacterial activity test of lime leaf essential oil cream (Citrus aurantyfolia, Swingle) against Staphylococus aureus bacteria was carried out by well diffusion method using Nutrient Agar (NA). The results of the data obtained were then subjected to statistical testing using SPSS with the One Way Anova test. The results showed that the essential oil cream preparations of lime leaves (Citrus aurartyfolia, Swingle) with varying concentrations of stearic acid fulfilled the physical quality test. The results of the antibacterial test for cream preparations showed antibacterial activity with the results of the diameter of the bacterial inhibition zone at F1 (-), F2 (14.83 mm), F3 (16.16 mm), and F4 (17.93 mm) and classified as having high inhibitory activity. strong. Key words : Lime Leaves (Citrus auratyfolia, Swingle), essential oil, anti-acne cream, Antibacterial, Staphylococus aureus
Item Type: | Thesis (Skripsi) |
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Uncontrolled Keywords: | Lime Leaves (Citrus auratyfolia, Swingle), essential oil, anti-acne cream, Antibacterial, Staphylococus aureus |
Subjects: | R Medicine > RS Pharmacy and materia medica R Medicine > RV Botanic, Thomsonian, and eclectic medicine |
Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
Depositing User: | Tifany Nur Arfiana |
Date Deposited: | 03 Jul 2023 04:29 |
Last Modified: | 03 Jul 2023 04:29 |
URI: | http://repo.setiabudi.ac.id/id/eprint/5940 |
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