Debbie Kavita, Melvi (2023) PENGUJIAN MUTU FISIK DAN PENETAPAN KADAR ASAM SALISILAT PADA KRIM WAJAH ANTI JERAWAT DARI MEREK X, Y, Z DENGAN METODE SPEKTROFOTOMETRI UV-VIS. Karya Tulis Ilmiah thesis, Universitas Setia Budi.
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Abstract
MELVI DEBBIE KAVITA, 2023, PENGUJIAN MUTU FISIK DAN PENETAPAN KADAR ASAM SALISILAT PADA KRIM WAJAH ANTI JERAWAT DARI MEREK X,Y, Z DENGAN METODE SPEKTROFOTOMETRI UV-VIS, KARYA TULIS ILMIAH, PROGRAM STUDI D-III ANALIS FARMASI DAN MAKANAN, FAKULTAS FARMASI, UNIVERSITAS SETIA BUDI. Dibimbing oleh apt. Anita Nilawati, M.Farm. Krim anti jerawat merupakan salah satu produk kosmetik yang sering digunakan untuk penyembuhan wajah berjerawat. Asam salisilat merupakan salah satu senyawa yang dapat digunakan, karena memiliki efek komedolitik ringan. Penelitian ini bertujuan untuk mengetahui mutu fisik dan kadar asam salisilat yang terkandung pada krim pagi anti jerawat. Penelitian ini menggunakan 3 sampel krim wajah anti jerawat dengan kriteria sediaan krim pagi, mencantumkan asam salisilat pada komposisi tetapi tidak mencantumkan persentase kadar asam salisilat pada kemasan sediaan tersebut. Sampel dilakukan pengujian mutu fisik meliputi uji organoleptik, pH, viskositas, homogenitas, daya sebar dan daya lekat yang dilanjutkan dengan penetapan kadar asam salisilat menggunakan metode spektrofotometri Uv-Vis. Hasil pengujian mutu fisik pada penelitian ini menunjukkan bahwa sampel memenuhi kriteria mutu fisik sediaan krim yang baik. Berdasarkan hasil uji viskositas dan daya lekat, sampel Z memiliki tingkat kekentalan dan daya lekat paling tinggi dibandingkan dengan sampel X dan Y, namun memiliki daya sebar paling rendah. Penelitian penetapan kadar asam salisilat, diperoleh panjang gelombang maksimum 529 nm dengan operating time pada menit ke - 19. Hasil penelitian sampel krim X, Y, dan Z secara berturut - turut didapatkan rata - rata kadar asam salisilat sebesar 1,25 % ; 3,18 % ; dan 2,8 % MELVI DEBBIE KAVITA, 2023, PHYSICAL QUALITY TESTING AND DETERMINATION OF SALICYLIC ACID LEVELS IN ANTI ACNE FACIAL CREAMS FROM BRAND X, Y, Z USING UV-Vis SPECTROPHOTOMETRY METHOD, SCIENTIFIC PAPERS, DIPLOMA OF PHARMACY AND FOOD ANALYSIS, FACULTY OF PHARMACY, SETIA BUDI UNIVERSITY. Supervised by apt. Anita Nilawati, M.Farm. Anti acne cream is a cosmetic product that is often used to cure facial acne. Salicylic acid is one of the compounds that can be used, because it has a mild comedolytic effect. This study aims to determine the physical quality and levels of salicylic acid contained in anti acne face creams. This study used 3 samples of anti acne face creams with the criteria for morning cream preparations, including salicylic acid in the composition but did not include the percentage of salicylic acid levels on the preparations of the packaging. Samples were tested for physical quality including organoleptic test, pH, viscosity, homogeneity, spreadability, and adhesion followed by determination of salicylic acid content using the UV-Vis spectrophotometry method. The results of physical quality testing in this study indicated that the samples met the physical quality criteria for good cream preparation. Based on the results of the viscosity and adhesion tests, sample Z showed the highest level of viscosity and adhesion compared to samples X and Y, but had the lowest spreadability. Research on the determination of salicylic acid levels, obtained a maximum wavelength of 529 nm with operating time in the 19th minute. The results of the research on cream samples X, Y, Z respectively, it was found that the average salicylic acid content was 1,25 % ; 3,18 % ; and 2,8 %.
| Item Type: | Thesis (Karya Tulis Ilmiah) |
|---|---|
| Uncontrolled Keywords: | Asam salisilat, uji mutu fisik, spektrofotometri UV-Vis |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Prodi D3 Analis Farmasi dan Makanan |
| Depositing User: | USB |
| Date Deposited: | 29 Feb 2024 04:23 |
| Last Modified: | 29 Feb 2024 04:23 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/6044 |
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