FORMULASI DAN UJI MUTU FISIK SEDIAAN KRIM NICOTINAMIDA DENGAN VARIASI EMULGATOR ASAM STEARAT DAN TRIETANOLAMIN

Ayuningrum, Anisa Dyah (2023) FORMULASI DAN UJI MUTU FISIK SEDIAAN KRIM NICOTINAMIDA DENGAN VARIASI EMULGATOR ASAM STEARAT DAN TRIETANOLAMIN. Karya Tulis Ilmiah thesis, Universitas Setia Budi.

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Abstract

ANISA, DYAH AYUNINGRUM, 2023. FORMULATION AND PHYSICAL QUALITY TEST NICOTINAMIDE CREAM WITH EMULSIFIERS VARIATION OF STEARIC ACID AND TRIETHANOLAMINE, SCIENTIFIC WRITING, FACULTY OF PHARMACY, UNIVERSITY SETIA BUDI, SURAKARTA. Supervised by Apt. Dewi Ekowati., S.Si., M.Sc. Nicotinamide is a drug that contains a type of vitamin B3 or niacin. The use of nicotinamide is widely used for the treatment of accumulated acne on the face and other inflammatory skin disorders. The purpose of this study is to find out the effect of stearic acid and triethanolamine emulsifiers variations on nicotinamide cream on the physical quality test of the cream. Nicotinamide with variations of emulsifier stearic acid and trictanolamine is made into cream preparations with 3 formulas, namely FI concentration of stearic acid and triethanolamine (17% : 1%), FII concentration of stearic acid and triethanolamine (16% : 2%), FIII concentration of stearic acid and triethanolamine (15% : 3%). Then each formula tested the physical quality of the cream in the form of organoleptic test, homogeneity test, viscosity test, spreadability test, adhesion test, pH test, cream type test, and stability test. Data were statistically analyzed using the Test of Homogeneity of Variances. Then proceed with the test (ANOVA). If the data has differences then Duncan's test is carried out. The results showed that variations in emulsifying stearic acid and triethanolamine had an effect on the physical quality of nicotinamide cream which included organoleptic tests, homogeneity tests, cream type tests, viscosity tests, spreadability tests, adhesion tests, pH tests, and stability tests. From the results of the physical quality test data of the cream, it shows that all formulas meet good cream standards.

Item Type:	Thesis (Karya Tulis Ilmiah)
Uncontrolled Keywords:	Cream, nicotinamide, stearic acid, triethanolamine, test of physical quality of cream
Subjects:	L Education > L Education (General)
Divisions:	Fakultas Farmasi > Prodi D3 Farmasi
Depositing User:	USB
Date Deposited:	05 Mar 2024 04:53
Last Modified:	05 Mar 2024 04:53
URI:	http://repo.setiabudi.ac.id/id/eprint/6105

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