UJI AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK ETANOL DAUN LARUNA (Chromolaena odorata L.) DAN DAUN SIRSAK (Annona muricata L.) TERHADAP BAKTERI Staphylococcus aureus

Darsa, Saskia Febrianty Putri (2024) UJI AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK ETANOL DAUN LARUNA (Chromolaena odorata L.) DAN DAUN SIRSAK (Annona muricata L.) TERHADAP BAKTERI Staphylococcus aureus. Skripsi thesis, Universitas Setia Budi.

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Abstract

SASKIA FEBRIANTY PUTRI DARSA, 2023, TESTING THE ANTIBACTERIAL ACTIVITY OF A COMBINATION OF ETHANOL EXTRACT OF LARUNA LEAVES (Chromolaena odorata L) AND SOURSOP LEAVES (Annona muricata L) AGAINST THE BACTERIA Staphyloccocus aureus, THESIS, BARGAIN STUDY PROGRAM OF PHARMACY, SETIA BUDI UNIVERSITY SURAKARTA. Supervised by Dr. apt. Ismi Rahmawati, M.Si and Desi Purwaningsih, S.Pd., M.Si. Laruna leaves and soursop leaves are plants that contain saponin compounds, flavonoids, tannins, triterpenoids, steroids, essential oils which have antibacterial effects. Based on previous research, Laruna leaves and Soursop leaves have antibacterial activity against Staphyloccocus aureus bacteria. This research aims to test and prove the antibacterial activity of a combination of ethanol extracts of Laruna leaves and Soursop leaves against Staphylococcus aureus. Laruna leaves and soursop leaves were extracted using the maceration method with 96% ethanol as the solvent. The tests carried out were phytochemical screening, antibacterial activity testing using dilution and diffusion methods (disc method). The concentration ratio used was 1:1, 1:2, 2:1 to test antibacterial activity with the positive control gentamicin. The results of the research showed that the combination of ethanol extracts of laruna leaves and soursop leaves had antibacterial activity on Staphylococcus aureus with a minimum kill concentration of 6.25% and 12.5% and the most effective ratio of the combination of ethanol extracts of laruna leaves and soursop leaves was 2:1 with the resulting combination effect pattern being synergistic. SASKIA FEBRIANTY PUTRI DARSA, 2023, UJI AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK ETANOL DAUN LARUNA (Chromolaena odorata L) DAN DAUN SIRSAK (Annona muricata L) TERHADAP BAKTERI Staphylococcus aureus, SKRIPSI, PROGRAM STUDI S1 FARMASI, UNIVERSITAS SETIA BUDI SURAKARTA. Dibimbing oleh Dr. apt. Ismi Rahmawati,M.Si dan Desi Purwaningsih, S.Pd., M.Si. Daun Laruna dan daun Sirsak merupakan tanaman yang mengandung senyawa saponin, flavonoid, tanin, triterpenoid, steroid, minyak atsiri yang memiliki efek sebagai antibakteri. Berdasarkan penelitian sebelumnya daun Laruna dan daun Sirsak mempunyai aktivitas antibakteri terhadap bakteri Staphyloccocus aureus. Penelitian ini bertujuan untuk menguji dan membuktikan aktivitas antibakteri kombinasi ekstrak etanol daun Laruna dan daun Sirsak terhadap Staphylococcus aureus. Daun Laruna dan daun Sirsak diekstraksi menggunakan metode maserasi dengan etanol 96% sebagai pelarutnya. Uji yang dilakukan yaitu skrining fitokimia, pengujian aktivitas antibakteri menggunakan metode dilusi dan difusi (metode cakram). Perbandingan konsentrasi yang digunakan adalah 1:1, 1:2, 2:1 untuk pengujian aktivitas antibakteri dengan kontrol positif gentamicin. Hasil dari penelitian menunjukan bahwa kombinasi ekstrak etanol daun laruna dan daun sirsak memiliki aktivitas antibakteri pada Staphylococcus aureus dengan konsentrasi bunuh minimum sebesar 6,25% dan 12,5% dan perbandingan paling efektif dari kombinasi ektrak etanol daun laruna dan daun sirsak yaitu 2:1 dengan pola efek kombinasi yang dihasilkan adalah sinergis

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Antibakteri, kombinasi, daun Laruna, daun Sirsak, Staphylococcus aureus. Antibacterial, combination, Laruna leaves, Soursop leaves, Staphyloccocus aureus
Subjects:	Q Science > Q Science (General)
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	USB
Date Deposited:	18 Nov 2024 04:07
Last Modified:	18 Nov 2024 04:07
URI:	http://repo.setiabudi.ac.id/id/eprint/6533

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