UJI ANTIPIRETIK KOMBINASI EKSTRAK ETANOL HERBA SAMBIILOTO (Andrographis paniculata Burm.f. Nees.) DAN EKSTRAK ETANOL HERBA MENIRAN (Phyllanthus niruri L.) PADA MENCIT (Mus musculus) JANTAN

Gustiati, Irma (2017) UJI ANTIPIRETIK KOMBINASI EKSTRAK ETANOL HERBA SAMBIILOTO (Andrographis paniculata Burm.f. Nees.) DAN EKSTRAK ETANOL HERBA MENIRAN (Phyllanthus niruri L.) PADA MENCIT (Mus musculus) JANTAN. Karya Tulis Ilmiah thesis, Universitas Setia Budi Surakarta.

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Abstract

Indonesia's tropical natural wealth allows many useful plants to thrive among the sambiloto (Andrographis paniculata Burm.f. Nees.) And meniran (Phyllanthus niruri L.) which are empirically used as external medicine and internal medicine. This study aims to determine the effect of the combination of extract and determine the effective combination dose as antipyretic. The extraction method used was maceration with 70% ethanol solvent. Mice were divided into 8 treatment groups. Each mouse-induced Pentabio vaccine (DPT-HB-HIB) with a dose of 0.2 ml / 20 g BB. The negative control group was given Na CMC, the positive control group was given paracetamol and the extract group with the combined dosage as follows group 1 (100: 0)% / 20 g BB, group 2 (0: 100)% / 20 g BB, group 3 (100 : 100)% / 20 g BB, group 4 (50: 50)% / 20 g BB, group 5 (75: 25)% / 20 g BB and group 6 (25: 75)% / 20 g BB. Temperature measurements were carried out for 3 hours at 30 minute intervals. The measurement data were analyzed statistically using 2 Independent Samples method. The result of research showed that the combination of extracts have antipyretic effects. The effective combination for antipyretic agent was 75% sambiloto and 25% meniran herb ethanol extracts (75 : 25) %/20 g BB. Keywords: Sambiloto, Meniran, Ethanol extract, Antipyretic

Item Type:	Thesis (Karya Tulis Ilmiah)
Uncontrolled Keywords:	Sambiloto, Meniran, Ethanol extract, Antipyretic
Subjects:	R Medicine > R Medicine (General)
Divisions:	Fakultas Farmasi > Prodi D3 Farmasi
Depositing User:	Rohma Tri Wardani
Date Deposited:	23 Feb 2019 03:19
Last Modified:	23 Feb 2019 03:19
URI:	http://repo.setiabudi.ac.id/id/eprint/662

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