UJI AKTIVITAS LARVASIDA EKSTRAK ETANOL, FRAKSI n-HEKSANA, FRAKSI ETIL ASETAT, DAN FRAKSI AIR DAUN TAPAK DARA (Catharanthus roseus (L.) G.Don) TERHADAP LARVA NYAMUK Aedes aegypti

Meilinasari, Mutiya Nur Rizky (2018) UJI AKTIVITAS LARVASIDA EKSTRAK ETANOL, FRAKSI n-HEKSANA, FRAKSI ETIL ASETAT, DAN FRAKSI AIR DAUN TAPAK DARA (Catharanthus roseus (L.) G.Don) TERHADAP LARVA NYAMUK Aedes aegypti. Skripsi thesis, Universitas Setia Budi Surakarta.

	Text INTISARI.pdf Download (89kB)
	Text SKRIPSI MUTIYA.pdf Download (2MB)

Abstract

Dengue fever is one of the endemic diseases and major problem in Indonesia. Catharanthus roseus contains an alkaloid, flavonoid, saponin, and tanins compound as biolarvacides. The present study aimed to determine larvacidal activity extract and fraction of Catharanthus roseus leaf. Plant powder was extracted using Soxhlet apparatus with ethanol 70%. The ethanol extract of Catharanthus leaf fractionated with n-hexane, ethyl acetate, and water. Extract and fraction was tested at 5 different concentrations of 1000, 500, 250, 125, and 62,5 ppm. Larvacidal activity test against III instar larvae of Aedes aegypti was done using 25 larvae for each treatment exposed for 24 hours and analyzed using probit analysis to determine the LC50 value. The result showed larvacidal activity on larvae of Aedes aegypti mosquitoes with LC50 value of ethanol extract, n-hexane fraction, ethyl acetate fraction, and aqueous fraction of Catharanthus leaf against 3rd instar larvae of Aedes aegypti were 865,617 ; 782,308 ; 419,301; and 3212,097 ppm. Ethyl acetate fractions of ethanol extract of Catharanthus leaf showed to have highest larvacidal activity against 3rd instar larvae of Aedes aegypti mosquitoes. Keywords : Catharanthus roseus leaf, ethyl acetat fraction, larvacidal, Aedes aegypti

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Catharanthus roseus leaf, ethyl acetat fraction, larvacidal, Aedes aegypti
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	23 Feb 2019 04:21
Last Modified:	23 Feb 2019 04:21
URI:	http://repo.setiabudi.ac.id/id/eprint/867

Actions (login required)

View Item