UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL 70%, FRAKSI n-HEKSANA, ETIL ASETAT, DAN AIR DARI DAUN CABE RAWIT (Capsicum frutescens L. ) TERHADAP BAKTERI Klebsiella pneumoniae ATCC 10031

Anggraheni, Natalia Marta (2017) UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL 70%, FRAKSI n-HEKSANA, ETIL ASETAT, DAN AIR DARI DAUN CABE RAWIT (Capsicum frutescens L. ) TERHADAP BAKTERI Klebsiella pneumoniae ATCC 10031. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

The reason of respiratory tract infection is the exposed of microorganism to the respiratory tract. One of the main causes microorganism ISP is Klebsiella pneumoniae bactery. The utilization of medical plans as a antibiotic replacement were necessary because increase in bactery resistant of antibiotic. Cayenne leaves was contain tanins, saponins, flavonoids, and alkaloids. The purpose of this research was to know the antibacterial activities of ethanol extract 70%, the fraction of n-heksane, ethyl acetate fraction, and the water fraction of cayenne Leaves (Capsicum frutescens L.) of Klebsiella pneumoniae ATCC 10031. The cayenne Leaves powder was extracted by remasereted method with the etanolic 70%, and then it was fractionated by solvent n-heksane, ethyl acetate, and water. Antibacterial activity test was performed using diffusion and dilution methods. The concentration used in the diffusion method was 50%, 25% and 12,5% aimed to determine the most active fraction. The most active fraction is continued dilution test to determine the MIC and MBC with concentration 50%, 25%, 12,5%, 6,25%, 3,12%, 1,56%, 0,78%, 0,39%, 0,2%, 0,1%. Statistical analysis using oneway ANOVA to determine whether there is a significant difference between the test preparation. The results showed that all the fractions and extracts cayenne leaves had antifungal activity. Most active fraction cayenne leaves that is a water fraction with a value of 25% of MCK. Key words: (Capsicum frutescens L.), fraction of n-hexane, ethyl acetate fraction, fraction of water, Klebsiella pneumoniae ATCC 10031

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	(Capsicum frutescens L.), fraction of n-hexane, ethyl acetate fraction, fraction of water, Klebsiella pneumoniae ATCC 10031
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Herera Gadys USB
Date Deposited:	25 Feb 2019 02:59
Last Modified:	25 Feb 2019 02:59
URI:	http://repo.setiabudi.ac.id/id/eprint/968

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