PENGARUH KOMBINASI GELLING AGENT CARBOPOL 940 DAN CMC Na TERHADAP MUTU FISIK GEL EKSTRAK ETANOL KULIT BUAH MANGGIS (Garcinia mangostana L.)

Rohmah, Nur Fitriya (2019) PENGARUH KOMBINASI GELLING AGENT CARBOPOL 940 DAN CMC Na TERHADAP MUTU FISIK GEL EKSTRAK ETANOL KULIT BUAH MANGGIS (Garcinia mangostana L.). Karya Tulis Ilmiah thesis, Universitas Setia Budi Surakarta.

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Abstract

Pericarp mangosteen (Garcinia mangostana L.) is one of the plants that has been shown to have anti-inflamation activity because it contains xanthones compounds, to facilitate the use of mangosteen peel extract to be effective and stable, it is necessary to make gel preparations. Research aimed to know the combination of gelling agent to the test physical quality of the gel and find out the best combination of gelling agent. Pericarp mangosteen gel was prepared using 2 % ethanolic extract of pericarp mangosteen with combination gelling agent of Carbopol 940 and CMC Na , the formula I (1 gram Carbopol 940 and CMC Na 0 gram), the formula 2 (0,5 gram Carbopol 940 and CMC Na 0,5 gram), formula 3 (0 gram Carbopol 940 and CMC Na 1 gram). And then the gel was tested for its physical quality test and than data was statistically analyzed using one-way Anova at 95% confidence. The result of the research prove that the etanolic extract of pericarp mangosteen (Garcinia mangstana L.) with a combination gelling agent Carbopol 940 and CMC Na gives a not significant difference to the physical quality of the gel and combination gelling agent Carbopol 940 1 gram dan CMC Na at formulation I provides good and stable physical quality including spreadability, adhesion and viscosity. Kata kunci: Gel, ethanolic extract of pericarp mangosteen, gelling agent, Carbopol 940, CMC Na

Item Type:	Thesis (Karya Tulis Ilmiah)
Uncontrolled Keywords:	Gel, ethanolic extract of pericarp mangosteen, gelling agent, Carbopol 940, CMC Na
Subjects:	R Medicine > RM Therapeutics. Pharmacology
Divisions:	Fakultas Farmasi > Prodi D3 Farmasi
Depositing User:	Mrs NOVI HANDAYANI
Date Deposited:	12 Nov 2019 07:36
Last Modified:	12 Nov 2019 07:36
URI:	http://repo.setiabudi.ac.id/id/eprint/3793

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