RAHMAWATI, Pristovia Oksinanida (0201) PENGARUH EKSTRAK ETANOL BUAH DUWET (Syzygium cumini L.) TERHADAP KADAR GLUKOSA DARAH DAN KADAR MALONDIALDEHID PADA TIKUS DIABETES YANG DIINDUKSI ALOKSAN. Skripsi thesis, Universitas Setia Budi Surakarta.
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Abstract
Duwet fruit contains of flavonoid compounds and act as antioxidants are expected to potentially lower blood glucose levels and level of MDA through preventing lipid oxidation. The purpose of this research is to determine the effective dose of ethanol extract of duwet fruit can decrease blood glucose levels and the level of MDA in rats diabetes that induced aloksan. This research uses 30 male rats were divided into 6 groups. Group I as a normal control; group II as a diabetic control (alloxan); the group III as control group (glibenclamide); the groups IV, V and VI as a test group to extract ethanol duwet fruit with a dosage of 100 mg/kg BW, 200 mg/kg BW and 400 mg/kg BW for 14 days. In this research do measure body weight of rats and blood glucose levels by using glucose oxidase (GOD-PAP) methode. The measurement of the level of MDA was done on day 5th. The results showed that there was increase in body weight after diabetic rats were given treatment with ethanol extract of duwet fruit. The test group ethanol extract duwet fruit 100 mg/kg BW and 200 mg/kg BW decreased blood glucose and the MDA level while dose 400 mg/kg BW experience decreased blood glucose and the MDA level similar to the control group (glibenclamide). The most effective dose in lowering blood glucose levels and the MDA level is the dose of 400 mg/kg BW. Key Words : Duwet fruit, antihiperglikemia, malondialdehid, antioxidants.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | Duwet fruit, antihiperglikemia, malondialdehid, antioxidants. |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
| Depositing User: | Tifany Nur Arfiana |
| Date Deposited: | 25 Feb 2019 03:19 |
| Last Modified: | 25 Feb 2019 03:19 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/1082 |
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