PENGARUHPEMBERIAN EKSTRAK ETANOL DAUN MANGGIS (GarciniamangostanaL.) TERHADAP KADAR HDL DANLDL TIKUSPUTIH JANTAN GALUR WISTAR YANG DIBERIDIETTINGGI LEMAK

ANGGRAINI, Diyah Ayu (2016) PENGARUHPEMBERIAN EKSTRAK ETANOL DAUN MANGGIS (GarciniamangostanaL.) TERHADAP KADAR HDL DANLDL TIKUSPUTIH JANTAN GALUR WISTAR YANG DIBERIDIETTINGGI LEMAK. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Research on the effect of ethanolic extract of leaves mangosteen (Garcinia mangostana L.) to decrease LDL and increase HDL blood serum white male rats aimed to determine the effect of leaf extract mangosteen (Garcinia mangostana L.) of HDL and LDL white male rats wistar strain. Objects in this study were white rats weighing as much as 35 heads with 150 – 200 grams aged 2 – 3 months. All the rats were divided into 6 groups randomly BR II then fed every day. Each groups consisted of 5 rats. Group I normal control was given BR II. Groups II negative control group was given 0,5% cmc. Group III as a positive control group with administration of simvastatin. Group IV, V, VI the extract dose 87.5 mg/kg BW, 175 mg/kg BW, 350 mg/kg BW. Whole rat measured HDL and LDL before and after of treatment. The results showed that all three doses is able to raise HDL and lower LDL. The effective dose is a dose of 350 mg/kg BW. Mangosteen leaf extract significantly influence the levels of HDL and LDL. Keywords : leaf extract of mangosteen, LDL cholesterol, HDL cholesterol, white male wistar rats.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: leaf extract of mangosteen, LDL cholesterol, HDL cholesterol, white male wistar rats.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 30 Sep 2019 04:07
Last Modified: 30 Sep 2019 04:07
URI: http://repo.setiabudi.ac.id/id/eprint/1357

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