UJI TOKSISITAS SUBKRONIK ESKTRAK METANOL UMBI SARANG SEMUT (Hydnophytum formicarum Jack.) TERHADAP HISTOPATOLOGI ORGAN LAMBUNG PADA TIKUS PUTIH JANTAN (Rattus novergicus)

Bambut, Wensislaus E. (2013) UJI TOKSISITAS SUBKRONIK ESKTRAK METANOL UMBI SARANG SEMUT (Hydnophytum formicarum Jack.) TERHADAP HISTOPATOLOGI ORGAN LAMBUNG PADA TIKUS PUTIH JANTAN (Rattus novergicus). Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

The use of tuber sarang semut as an ingredient of drugs has been mostly done among community and proved to give a good effect for a variety of ailments, but the security level is not yet known when worn in a long period of time. Test security level needs to be done and one of them is through a test of toxicity of sub kronik. This research aims to find out whether there are effects on the awarding of the methanol extract of tuber Ant (Hydnophytum formicarum) given orally against weight gain and stomach organ histopathology in mice. The research on test animals used are white males as much as 40 rats tails which are divided in 4 groups and each group of 10 rats. The dose I 0, 135 g/KgBB, doses of 0, 27g II/III dose KgBB, 0, 54 g/KgBB and control by administering doses of aquadestsilata. Testing conducted for 3 months in a row. Results of the research note that the granting of the methanol extract of tuber Ant (Hydnophytum formicarum Jack.) given orally for 3 months can lose weight the rats as well as give the toxic effects of erosion and congestion on the wall of the stomach of rats observed in histopathology. Key words: sub kronik , extract methanol, sarang semut, histopathology

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: sub kronik , extract methanol, sarang semut, histopathology
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 18 Feb 2020 03:52
Last Modified: 18 Feb 2020 03:52
URI: http://repo.setiabudi.ac.id/id/eprint/2240

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