PENGARUH KOMBINASI GELLING AGENT CARBOPOL 940 DAN TRAGAKAN TERHADAP MUTU FISIK GEL EKSTRAK ETANOL KULIT BUAH MANGGIS (Garcinia mangostana L.)

Hungga, Renata Martina (2019) PENGARUH KOMBINASI GELLING AGENT CARBOPOL 940 DAN TRAGAKAN TERHADAP MUTU FISIK GEL EKSTRAK ETANOL KULIT BUAH MANGGIS (Garcinia mangostana L.). Karya Tulis Ilmiah thesis, Universitas Setia Budi Surakarta.

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Abstract

Mangosteen (Garcinia mangostana L.) is a plant which one of them has anti-inflammatory activity. The mangosteen peel is extracted with 70% ethanol, then formulated into pharmaceutical preparations, namely gel so that its use is not easily sticky, easy to apply, easy to wash and does not leave a layer of oil on the skin. The purpose of this study was to determine the effect of the carbopol 940 gelling agent combination and tragedy and find out which formula was the best for the physical quality test of the mangosteen peel ethanol extract gel. The making of the mangosteen peel extract ethanol gel in this study used 2 grams of ethanol extract of mangosteen peel with different gelling agent carbopol 940 and tragacacant combination, formula 1 (carbopol 940 1 gram), formula 2 (carbopol 940 0.5 gram and tragacanth 0,5 grams), formula 3 (tragakan 1 gram). After that the gel in the physical quality test includes: organoleptic test, homogeneity test, viscosity test, sticky power test, dispersion test, pH test observed for three weeks. Data were analyzed statistically one-way ANOVA with a confidence level of 95%. The results showed that the ethanol extract of mangosteen peel (Garcinia mangostana L.) with a gelling agent carbopol 940 combination and tragacanth did not affect the physical quality of gel preparations so as to provide good physical quality of the ethanol extract of mangosteen peel. And all three formulas provide a stable stability test on storage. Keywords: gel, mangosteen peel ethanol extract, carbopol 940, tragacanth

Item Type:	Thesis (Karya Tulis Ilmiah)
Uncontrolled Keywords:	gel, mangosteen peel ethanol extract, carbopol 940, tragacanth
Subjects:	Q Science > QK Botany
Divisions:	Fakultas Farmasi > Prodi D3 Farmasi
Depositing User:	Mrs NOVI HANDAYANI
Date Deposited:	16 Nov 2019 02:25
Last Modified:	16 Nov 2019 02:25
URI:	http://repo.setiabudi.ac.id/id/eprint/3800

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