UJI AKTIVITAS ANTIBAKTERI SEDIAAN OBAT KUMUR (mouthwash) EKSTRAK BIJI PINANG (Areca catechu L.) TERHADAP Streptococcus mutans ATCC 25175 SECARA in vitro

Wunga, Noviani Adumiati (2019) UJI AKTIVITAS ANTIBAKTERI SEDIAAN OBAT KUMUR (mouthwash) EKSTRAK BIJI PINANG (Areca catechu L.) TERHADAP Streptococcus mutans ATCC 25175 SECARA in vitro. Skripsi thesis, Universitas Setia Budi.

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Abstract

The mouth is an ideal place for the growth and development of microorganism. Streptococcus mutans ATCC 25175 is a normal flora that lives in the oral cavity, but in excess amounts is the main causative agent for dental caries. Control of dental caries can be by brushing teeth using toothpaste or using mouthwash. Areca nuts contain alkaloid compounds, flavonoids, polyphenols, tannins, and saponins. The aim of this study was to determine the antibacterial activity of areca nut extract mouthwash against Streptococcus mutans ATCC 25175 bacteria. Areca nuts were extracted by maceration with 70% ethanol. Ethanol extract of areca nuts were made in a mouthwash formula with a concentration of 1.5, 3, and 4.5%. Testing the physical quality of mouthwash formula includes physical form testing, clarity test, viscosity test, and pH test. The inhibitory testing method uses the disc diffusion method with a sample of Streptococcus mutans ATCC 25175 in vitro. The results of testing the antibacterial activity of areca seed extract and mouthwash formula with disc diffusion method showed indicated inhibition by the presence of clear areas around the disc. The average inhibitory diameter was greatest from areca seed extract is 14.08 mm at a concentration of 4.5%. The average inhibitory diameter of the formula of mouthwash is 14.33 mm in formula 3 with 4.5% areca seed extract concentration. Key words : Streptococcus mutans, areca nut, mouthwash, disc diffusion.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Streptococcus mutans, areca nut, mouthwash, disc diffusion.
Subjects:	Q Science > QR Microbiology
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	20 Jan 2020 04:26
Last Modified:	20 Jan 2020 04:26
URI:	http://repo.setiabudi.ac.id/id/eprint/4054

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