AKTIVITAS PENINGKATAN DAYA INGAT EKSTRAK ETANOL DAN FRAKSI-FRAKSI RIMPANG TEMULAWAK (Curcuma xanthorrhiza Roxb) PADA MENCIT (Mus musculus)

Rahmadina, Adinda Putri Suci (2021) AKTIVITAS PENINGKATAN DAYA INGAT EKSTRAK ETANOL DAN FRAKSI-FRAKSI RIMPANG TEMULAWAK (Curcuma xanthorrhiza Roxb) PADA MENCIT (Mus musculus). Skripsi thesis, Universitas Setia Budi.

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Abstract

Temulawak rhizome (Curcuma xanthorrhiza Roxb) is a plant that contains curcumin. Curcumin is thought to be able to improve memory because it can reduce oxidative damage caused by free radicals. This study aims to determine the effect of the extract and fraction of temulawak rhizome) on improving memory in white mice, which had been induced with plumbum acetate. Testing memory in this study using the radial arm maze method. Parameters that can be seen from the test are the percent error number B and latency time. A total of 30 mice in this test were divided into 6 groups, namely negative control (Na CMC), positive control (Ginkgo Biloba), ethanol extract of temulawak rhizome, ethyl acetate fraction, n-hexane fraction, and water fraction. The results showed that the administration of the extract and the ethyl acetate fraction of temulawak rhizome was able to improve memory by reducing the B error rate and increasing latency time compared to the n-hexane fraction and the water fraction. Key words : Curcumin, % error rate B and latency time, memory,

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: Curcumin, % error rate B and latency time, memory,
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 21 Jul 2022 03:57
Last Modified: 21 Jul 2022 03:57
URI: http://repo.setiabudi.ac.id/id/eprint/4924

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