UJI AKTIVITAS EMUGEL MINYAK ATSIRI RIMPANG JERINGAU (Acorus calamus L) TERHADAP BAKTERI Staphyloccocus aureus ATCC 25923 PENYEBAB JERAWAT

Permatasari, Anisa Putri (2021) UJI AKTIVITAS EMUGEL MINYAK ATSIRI RIMPANG JERINGAU (Acorus calamus L) TERHADAP BAKTERI Staphyloccocus aureus ATCC 25923 PENYEBAB JERAWAT. Skripsi thesis, Universitas Setia Budi.

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Abstract

Acne can occur due to accumulation of dirt in the pores of the skin that attacks the face, chest, back, and upper arms. One of the causes of acne is Staphylococcus aureus bacteria. Jeringau rhizome contains 85% asarone, 3.45% cis methyl isoeugenol, 1.92% cyclohexene which can act as antibacterial. This study aims to determine the quality of essential oils and to formulate emulgel preparations from jeringau rhizome essential oil and to test the physical properties, as well as antibacterial activity against Staphylococcus aureus ATCC 25923. Jeringau rhizome essential oil was obtained from online sales circulating in Indonesia for identification oil stain, compound content with GC-MS, spesific gravity, refractive index, and oil soluble. Jeringau rhizome essential oil was formulated into 3 formulations with different concentrations of 6%, 8%, and 10%. Emulgel preparations in each formula were tested for organoleptic, pH, viscosity, spreadability, adhesion, stability, and antibacterial activity of Staphylococcus aureus ATCC 25923. The data were statistically analyzed using SPSS application with One Way ANOVA test. The results showed that the jeringau rhizome essential oil emulgel preparation had good physical quality and was stable in the stability test, and had antibacterial activity against S. aureus ATCC 25923 with an inhibitory zone at a concentration of 6; 8; and 10% is 11.56; 22.11; and 28.54 mm. The results showed that the most active emulgel of jeringau rhizome essential oil had antibacterial activity at a concentration of 10%. Keywords: Acorus calamus L, essential oil, emulgel, antibacterial, acne, Staphylococcus aureus.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Acorus calamus L, essential oil, emulgel, antibacterial, acne, Staphylococcus aureus.
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	21 Jul 2022 03:57
Last Modified:	21 Jul 2022 03:57
URI:	http://repo.setiabudi.ac.id/id/eprint/4936

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