Rinawati, Aprilia (2021) STUDI LITERATUR RASIONALITAS DAN POLA SENSITIVITAS BAKTERI Staphylococcus aureus PENYEBAB INFEKSI GANGREN DIABETES MELITUS TERHADAP ANTIBIOTIK. Skripsi thesis, Universitas Setia Budi.
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Abstract
Diabetic gangrene can be treated with antibiotics. The use of antibiotics must be done rationally. Antibiotic sensitivity patterns know which antibiotics have become resistant. The purpose of this literature study is to determine the relationship between rationality and patterns of antibiotic sensitivity in bacteria that cause gangrene infection The research was conducted using a literature study method using journals obtained through journal sites such as search engines Scopus, Google Scholar, ScienceDirect, NCBI, PubMed, Oxford Academics, Cambridge, and Sprinkle link published between 2009-2021, obtained journals as many as 13 journals extracted from 99 existing journals. This literature study was carried out in several stages, namely, formulating problems, collecting data, extracting data, synthesizing data, and compiling a thesis. The results of the literature study rationality of antibiotic use is precise indication, appropriate drug and appropriate patient. Antibiotics that are resistant in several hospitals in Indonesia are ceftriaxone, cotrimoxazole, benzylpenicillin erythromycin, ampicillin, cloramfenicol cefoperazone, meropenem, cefixime, gentamicin, ceftazidime, ciprofloxacin, streptomycin, lincomycin, and cefotaxime. The mechanism that bacteria have in developing resistance is by enzymatic modification, changes in PBP structure, pump protein production, and changes in antibiotic targets. Keywords: gangrene, resistance mechanisms, Rationality, sensitivity, Staphylococcus aureus,
Item Type: | Thesis (Skripsi) |
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Uncontrolled Keywords: | gangrene, resistance mechanisms, Rationality, sensitivity, Staphylococcus aureus, |
Subjects: | R Medicine > RS Pharmacy and materia medica |
Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
Depositing User: | Tifany Nur Arfiana |
Date Deposited: | 21 Jul 2022 03:57 |
Last Modified: | 21 Jul 2022 03:57 |
URI: | http://repo.setiabudi.ac.id/id/eprint/4937 |
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