Sari, Endah Purnama (2021) UJI AKTIVITAS HEPATOPROTEKTOR EKSTRAK DAN FRAKSI DAUN JAMBU MONYET (Anacardium occidentale) TERHADAP PARAMETER KADAR SGPT DAN SGOT TIKUS PUTIH YANG DIINDUKSI ALKOHOL 30%. Skripsi thesis, Universitas Setia Budi.
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Abstract
Liver disease can be caused by many factors, one of which is alcohol when alcohol is consumed for a long time and in a certain amount or volume. Specific indicators of liver cell disease is by increasing levels of SGPT and SGOT. This study was to determine the hepatoprotective activity of cashew leaves extract and fraction on SGPT & SGOT levels and to see the liver histology damage of 30% alcohol-induced white rats. This study used seven treatment groups, first the normal group, the negative group, the Curcuma positive group, the extract group, the water fraction group, the n-hexane fraction group, and the ethyl acetate fraction group. On days 0 and 16, SGPT and SGOT levels were measured using a photometer. On the 16th day, one animal in each group was dissected and assessed by the Hispatology Manja Roenigk Scoring. The data of SGPT and SGOT levels were used for the ANOVA statistical test The hepatoprotector activity of the extract and water fraction of cashew leaves showed an increase in SGPT & SGOT levels and the percentage of liver damage was comparable to the Curcuma positive group. The cashew leaves water fraction group had higher hepatoprotective activity than the extract group. Key words: alcohol, cashew leaves, hepatoprotector, histopathology, SGPT&SGOT.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | alcohol, cashew leaves, hepatoprotector, histopathology, SGPT&SGOT. |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
| Depositing User: | Tifany Nur Arfiana |
| Date Deposited: | 21 Jul 2022 03:58 |
| Last Modified: | 21 Jul 2022 03:58 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/4965 |
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