UJI AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL DAUN SIRIH MERAH (Piper crocatum) TERHADAP TIKUS PUTIH JANTAN INDUKSI PUTIH TELUR

Puspaningtyas, Anida (2021) UJI AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL DAUN SIRIH MERAH (Piper crocatum) TERHADAP TIKUS PUTIH JANTAN INDUKSI PUTIH TELUR. Karya Tulis Ilmiah thesis, Universitas Setia Budi.

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Abstract

Red betel leaf (Piper crocatum) is a traditional plants that empirically has various properties, one of which is anti-inflammatory. This research is intended to know the anti-inflammatory activity ethanol extract of red betel leaf and determine the effective dose ethanol extract of red betel leaf in male white rats induced by egg white. Red betel leaf was extracted by maceration method with ethanol 96%. Anti-inflammatory test used the method of measuring the volume of edema in rat paws. The test animals were divided into 5 groups, each group consisted of 5 rats, group 1 (negative control of 1% Na CMC), group 2 (positive control of diclofenac sodium), group 3 (extract dose 50mg/kgBW), group 4 (extract dose 100mg/kgBW), group 5 (extract dose 200mg/kgBW). Measurement of edema volume was carried out every 1 to 6 hours after treatment. The data obtained were analyzed using the ANOVA test, then the Tukey test was used to determine the differences between groups. The results of the research showed that ethanol extract of red betel leaf at doses of 50mg/kgBW, 100mg/kgBW, 200mg/kgBW had anti-inflammatory activity against white male rats induced by egg white. The effective dose of ethanol extract of red betel leaf in provided anti-inflammatory activity is 50mg/kgBW, 100mg/kgBB, 200mg/kgBW. Keyword: Red betel leaf, anti-inflammatory, egg white induced

Item Type:	Thesis (Karya Tulis Ilmiah)
Uncontrolled Keywords:	Red betel leaf, anti-inflammatory, egg white induced
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi D3 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	15 Aug 2022 06:50
Last Modified:	15 Aug 2022 06:50
URI:	http://repo.setiabudi.ac.id/id/eprint/5111

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