EVALUASI RASIONALITAS PENGGUNAAN OBAT ANTIHIPERTENSI PADA PASIEN GAGAL GINJAL KRONIK DI INSTALASI RAWAT INAP DI RSUD K.R.M.T WONGSONEGORO SEMARANG TAHUN 2020

Fatmawati, Aulia Dewi (2022) EVALUASI RASIONALITAS PENGGUNAAN OBAT ANTIHIPERTENSI PADA PASIEN GAGAL GINJAL KRONIK DI INSTALASI RAWAT INAP DI RSUD K.R.M.T WONGSONEGORO SEMARANG TAHUN 2020. Skripsi thesis, Universitas Setia Budi.

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Abstract

Chronic renal failure is a disease of decreased kidney function and glomerular filtration rate (eGFR) with an average value of <60ml/min per 1.73m² occurring for 3 months or more due to increased Renin-Angiotensin-Aldosterone- System (RAAS) activity, impaired synthesis of nitric oxide, and endotheliummediated vasodilation, thereby increasing systemic vascular resistance and blood pressure. Hypertension is a major risk factor for end-stage chronic renal failure (ESRD). The purpose of this study was to evaluate the use of antihypertensive drugs in patients with chronic renal failure at the inpatient installation of RSUD K.R.M.T Wongsonegoro Semarang. This study uses a non-experimental descriptive analysis study design with retrospective data collection carried out by tracing the patient's past data from the medical records of patients with chronic kidney failure accompanied by hypertension in 2020. A total of 27 samples of medical record data matched the inclusion criteria. The results showed that the largest population was 66.7% male and 33.3% female. The most widely used antihypertensive therapy pattern is combination therapy 89% and single 11%. Evaluation of correct diagnosis 100%, right indication 100%, right drug 70.4%, right dose 92.6%, right patient 100%, right time interval of administration 88.9%, right drug side effect 96.3%, route of administration the most drugs are oral 55.56% and intravenous administration of 44.44% are widely used loop diuretic antihypertensives. Keywords: evaluation, rationality, antihypertensive, chronic renal failure

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	evaluation, rationality, antihypertensive, chronic renal failure
Subjects:	R Medicine > RC Internal medicine
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	29 Sep 2022 04:38
Last Modified:	29 Sep 2022 04:38
URI:	http://repo.setiabudi.ac.id/id/eprint/5267

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