FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI Staphylococcus aureus SEDIAAN HAND SANITIZER SPRAY EKSTRAK BATANG BAJAKAH TAMPALA (Spatholobus littoralis Hassk) DENGAN VARIASI KONSENTRASI GLISERIN

RAHMIATI, NUR (2022) FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI Staphylococcus aureus SEDIAAN HAND SANITIZER SPRAY EKSTRAK BATANG BAJAKAH TAMPALA (Spatholobus littoralis Hassk) DENGAN VARIASI KONSENTRASI GLISERIN. Skripsi thesis, Universitas Setia Budi.

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Abstract

Staphylococcus aureus is a pathogenic bacterium that lives on the skin, causing various diseases such as skin infections, food poisoning, and bacteremia. Bajakah tampala is known to contain flavonoids, saponin, phenolic, and tannin compounds with antibacterial activity. The research objective was to formulate a hand sanitizer spray of bajakah tampala extract to test the physical properties, stability, and antibacterial activity against S. aureus bacteria. Bajakah tampala steel was extracted by the maceration method for 5 days with 70% ethanol solvent, and then identification of the compound was carried out. Bajakah tampala extract was formulated at 12.5% into 3 formulas with varying concentrations of glycerin, namely 5%, 7.5%, and 10%, and then tested for stability, physical quality including pH, viscosity, spraying pattern, and activity against S. aureus bacteria. The Shapiro-Wilk test was used to analyze the data, followed by the one-way ANOVA test. The results showed that the extract of bajakah tampala contained flavonoids, saponins and tannins. The preparation of hand sanitizer spray for bajakah extract without variations in glycerin concentration affected the stability, physical quality and antibacterial activity against S. aureus, and the best formula was the third formula with a variation of 10% glycerin concentration with an average inhibition diameter of 13.17 mm. The results of statistical tests on the antibacterial activity of the three formulas showed significantly different antibacterial activities. Kata kunci : Antibacterial, bajakah tampala, hand sanitizer, Staphylococcus aureus, glycerin

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Antibacterial, bajakah tampala, hand sanitizer, Staphylococcus aureus, glycerin
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	30 Nov 2022 02:57
Last Modified:	30 Nov 2022 02:57
URI:	http://repo.setiabudi.ac.id/id/eprint/5579

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