FORMULASI SEDIAAN GEL EKSTRAK UMBI BAWANG DAYAK (Eleutherine palmifolia (L) Merr.) SEBAGAI ANTIBAKTERI TERHADAP BAKTERI Staphylococcus aureus ATCC 25923

Melina, Sheila (2022) FORMULASI SEDIAAN GEL EKSTRAK UMBI BAWANG DAYAK (Eleutherine palmifolia (L) Merr.) SEBAGAI ANTIBAKTERI TERHADAP BAKTERI Staphylococcus aureus ATCC 25923. Skripsi thesis, Universitas Setia Budi.

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Abstract

Dayak onion bulbs (Eleutherine palmifolia (L) Merr.) is a plant that has antibacterial activity against Staphylococcus aureus bacteria, because it contains chemical compounds of flavonoids, tannins, steroids, phenolics, alkaloids, and saponins. The purpose of this study was to make a gel preparation from Dayak onion bulb extract which has good physical quality and stability and has activity against Staphylococcus aureus bacteria. In this study, Dayak onion bulbs were extracted using the meseration method with 96% ethanol as solvent. Dayak onion bulb extract was formulated to become a gel preparation with 3 variations of extract concentration 1%, 5%, and 10%. Furthermore, the gel preparations of each formula were tested for organoleptic, homogeneity, pH, viscosity, dispersibility, adhesion, stability and activity testing against Staphylococcus aureus bacteria. The data on the physical quality test and activity against Staphylococcus aureus were statistically analyzed using the Shapirow-Wilk test followed by the one way ANOVA test. The result of this research is that the gel preparation of Dayak onion bulb extract can be made into a gel that has good physical quality and stability. At a concentration of 1%, the Dayak onion extract gel has good physical quality and stability and has the most effective antibacterial activity with an inhibitory value of 17.83 mm. Keywords: Eleutherine palmifolia., antibacterial, gel, Staphylococcus aureus

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Eleutherine palmifolia., antibacterial, gel, Staphylococcus aureus
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	30 Nov 2022 02:59
Last Modified:	30 Nov 2022 02:59
URI:	http://repo.setiabudi.ac.id/id/eprint/5617

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