UJI AKTIVITAS ANTIDEPRESAN SENYAWA ISOMIRISTISIN TERHADAP AKTIVITAS LOKOMOTOR MENCIT PUTIH JANTAN (Mus musculus) DENGAN METODE OPEN FIELD TEST (OFT)

Nugroho, Vito (2023) UJI AKTIVITAS ANTIDEPRESAN SENYAWA ISOMIRISTISIN TERHADAP AKTIVITAS LOKOMOTOR MENCIT PUTIH JANTAN (Mus musculus) DENGAN METODE OPEN FIELD TEST (OFT). Skripsi thesis, Universitas Setia Budi.

	Text ABSTRAK.pdf Download (67kB)
	Text BAB I.pdf Download (520kB)
	Text BAB 2.pdf Restricted to Repository staff only Download (267kB) | Request a copy
	Text BAB 3.pdf Restricted to Repository staff only Download (146kB) | Request a copy
	Text BAB 4.pdf Restricted to Repository staff only Download (363kB) | Request a copy
	Text BAB 5.pdf Restricted to Repository staff only Download (7kB) | Request a copy
	Text DAFTAR PUSTAKA.pdf Download (17kB)
	Text LAMPIRAN.pdf Download (1MB)
	Text form pernyataan publikasi (1) (1).pdf Download (406kB)
	Text vito suket 30 maret.pdf Download (28kB)

Abstract

Isomyristicin is an isomerized product of myristicin and is thought to have the same activity as myristicin. Isomyristisin also has the same group as myristicin. The purpose of this study was to determine the antidepressant activity and the optimum dose of isomyristisin compound to increase the locomotor activity of malewhite mice (Mus musculus). The sample in this research is isomyristicin. This research used 30 male white mice which were divided into 6 groups. 5 mice each made normal control, negative control, positive control, control dose isomyristisin 1.5 mg/kgBW, 3 mg/kgBW, and 6 mg/kgBW. The methods used are Open Field Test (OFT) to measure the locomotor activity of male white mice. The normality distribution testwas carried out with the Saphiro Wilk test which was then followed by the One Way ANOVA test. The results showed that the dose of isomyristicin 1.5 mg/KgBW of mice was an optimum dose because the smallest dose was comparable to the positive control of amitriptyline 3.25 mg/KgBW of mice. The ability of isomyristin in the dose group of 1.5 mg / KgBB mice showed differences with normal control and negative control and there was no difference with positive control with sig values. p(>0.05) on LSD analysis. Key words : Isomyristicin, antidepressants, OFT

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Isomyristicin, antidepressants, OFT
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	03 Jul 2023 04:28
Last Modified:	03 Jul 2023 04:28
URI:	http://repo.setiabudi.ac.id/id/eprint/5963

Actions (login required)

View Item