UJI AKTIVITAS SEDIAAN GEL EKSTRAK ETANOL DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb) TERHADAP PENYEMBUHAN LUKA BAKAR BUATAN PADA KELINCI New Zealand

Oeleu, Krisantus Y. (2017) UJI AKTIVITAS SEDIAAN GEL EKSTRAK ETANOL DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb) TERHADAP PENYEMBUHAN LUKA BAKAR BUATAN PADA KELINCI New Zealand. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Burn injury is ranked 15th as the leading cause of death. The incidence of severe burns is about 95% more common in low- and middle-income countries accordingto World Health Organization (WHO) data in 2012. Pandanus fragnant (Pandanus amaryllifolius Roxb) can be used as an anti-inflammatory and antibacterial alternative because it has actives compounds such as flavonoid, tannin, saponins and alkaloids. The purpose of this research to proved the activity of ethanol extract of pandanus fragnant leaf gel preparation and to know which concentration that effective towards burn injury healing. Ethanol extract of pandanus fragnant leaf gel were made in three formula concentration 6.25%, 12.5% and 25%. Physical properties tested organoleptis, homogeneity, spreadability, viscosity, and adhesion. Test of wound healing activity is done on the back of the New Zealand rabbit rabbit. The results of wound healing measurements were analyzed statistically using variant analysis. Giving of ethanol extract pandanus fragrant leaf gel with concentration of 6.25%, 12.5%, 25% effect on healing burns. The result of statistic analysis showed that ethanol extract of pandan fragnant leaf gel preparation in 25% concentration showed wound healing effect that was not significantly different with positive control. Increased concentration of ethanol extract of pandan fragnant leaf gel preparation showed an increase of wound healing effect. Keywords: ethanol extract, pandanus fragrant leaf (Pandanus amaryllifolius R.), gel, burns, rabbit

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	ethanol extract, pandanus fragrant leaf (Pandanus amaryllifolius R.), gel, burns, rabbit
Subjects:	R Medicine > R Medicine (General)
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Rohma Tri Wardani
Date Deposited:	25 Feb 2019 03:39
Last Modified:	25 Feb 2019 03:39
URI:	http://repo.setiabudi.ac.id/id/eprint/1209

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