UJI AKTIVITAS ANTIBAKTERI KOMBINASI MINYAK ATSIRI RIMPANG BANGLE (Zingiber cassumunar Roxb.) dan DAUN KEMANGI (Ocimum basilicum L.) TERHADAP Staphylococcus aureus ATCC 25923

Anggrenie, Yanti (2017) UJI AKTIVITAS ANTIBAKTERI KOMBINASI MINYAK ATSIRI RIMPANG BANGLE (Zingiber cassumunar Roxb.) dan DAUN KEMANGI (Ocimum basilicum L.) TERHADAP Staphylococcus aureus ATCC 25923. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

The essential oil of bangle rhizome and basil leaves contains terpineol-4, sabinene, citral, linalool, eugenol and others. The purpose of this research is to know the activity of combination on essential oil bangle rhizome (Zingiber casumunar Roxb.) and basil leaves (Ocimum basilicum L.) as antibacterial to Staphylococcus aureus ATCC 25923. The method used in this research using dilution method with checkerboard system use the concentration of 25%; 12.5%; 6.25%; 3.125%; 1.56%; 0.78%. The checkerboard system use 48 tubes, 36 tubes containing a combination of both essential oils, while 6 tubes contain the essential oil of single bangle rhizome and 6 other tubes containing the essential oil of single basil leaves. MBC obtained was analyzed using Fractional Inhibitory Concentration Index (FIC Index) calculation to determine the effect combination of synergistic, additive or antagonist. The study results showed that essential oil of bangle rhizome, basil leaves and combination had antibacterial activity against Staphylococcus aureus ATCC 25923. The effective results on single essential oil of bangle rhizome with MBC 6.25%, basil leaves MBC 12.5% and the effective combination is at the concentration of essential oil bangle rhizome 0,78% with basil essential oil 3,125% and the concentration of essential oil rhizome bangle 1.56% with basil essential oil 1.56%. The combination of essential oil of rhizome bangle and basil leaf has a synergistic effect with the FIC index value of 0,3748 and 0.3744 (<0.5). Keywords: Staphylococcus aureus ATCC 25923, antibacterial, essensial oil, Zingiber cassumunar Roxb., Ocimum basilicum L.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Staphylococcus aureus ATCC 25923, antibacterial, essensial oil, Zingiber cassumunar Roxb., Ocimum basilicum L.
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Herera Gadys USB
Date Deposited:	25 Feb 2019 03:43
Last Modified:	25 Feb 2019 03:43
URI:	http://repo.setiabudi.ac.id/id/eprint/1282

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