LESTARI, Murni (2016) UJI EFEK LAKSATIF EKSTRAK ETANOL DAUN BAYAM MERAH ( Amaranthus tricolor., L. ) PADA TIKUS JANTAN GALUR WISTAR DENGAN METODE TRANSIT INTESTINAL. Skripsi thesis, Universitas Setia Budi Surakarta.
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Abstract
Red spinach plants (Amaranthus tricolor., L.) was folk medicinal plants which leaves represent an laxative effective medicine empirically on it. This research aims to find out an laxative effect of ethanol extract of red spinach and the most effective dose as the laxative. The research used intestinal transit methode with an experiment of white Wistar rats. The experimented rats were induced loperamid orally as much as 3 mg/kg BB every day for three days. The constipation rats were divided into five groups in homogeny. Continually the rats were given CMC 0.5%,with extract dose as much as 5 mg, 10 mg, 20 mg and Na.Dokusinat as much as 0.9 mg/200 g BB to the rats. They were remaited alone for 45 minutes and given marker as much as 1 ml for each rats. After 20 minutes, they were dissected and measured the length of their intestines that were passed by norit and the length of all intestines. The Result showed that all doses extract had a laxative effect. Extract 5 mg and 10 mg had the same laxative effect with Na.dokusinat. Extract 20 mg given the most laxative effective than Na.dokusinat. It was supposed that the effect of laxative comes from extract contain such as saponin with characteristic of detergensia, alkaloid, flavonoid and polifenol that can stimulate intestines. Key words: Red Spinach (Amaranthus tricolor.,L.). Laxative, Intestinal Transit Method.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | Red Spinach (Amaranthus tricolor.,L.). Laxative, Intestinal Transit Method. |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
| Depositing User: | Tifany Nur Arfiana |
| Date Deposited: | 01 Oct 2019 03:17 |
| Last Modified: | 01 Oct 2019 03:17 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/1424 |
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