Wulandari, Aprilia Rizki (2016) FORMULASI DAN UJI MUTU FISIK SUSPENSI KLORAMFENIKOL DENGAN VARIASI SUSPENDING AGENT PULVIS GUMMI ARABICI (PGA) DAN CARBOPOL P 934. Karya Tulis Ilmiah thesis, Universitas Setia Budi Surakarta.
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Abstract
Chloramphenicol is abroad spectrumantibiotic, with toxsic characteristic. Chloramphenicol is one of antibiotic thats not dissolve in water, so it made in the form of suspension. Pulvis Gummi Arabici and Carbopol is suspending agent that easilly soluble in water. This study is to determine the effect of suspending agent variation PGA and carbopol P 934 in the manufacture suspension chloramphenicol and to knowing consentration of PGA and carbopol 934to give the best physical chloramphenicolsuspension. Suspensionchloramphenicol made by four formula, 5% I PGA and 1,5% carbopol P 934 formula, 10% II PGA and 1,5% carbopol P 934 formula, 5% PGA and 3% carbopol P 934 formula, and 10% IV PGA ad 3% carbopol P 934. The test is include physical quality ( sedimentation volume measurement, viskosotas, easy or not to cast, redispersibility, PH ). Physical quality test observation is doing once a week. Data were analyzed statistically anova one direction with 95% confidence level. The result,chloramphenicol can make to be suspension. Availability suspensionchloramphenicol with consentration 5% PGA and 1,5% carbopol P 934, 10% PGA and 1,5% carbopol P 934, 5% PGA and 3% carbopol P 934, and 10% PGA and 3% carbopol is qualified physical quallity test suspension. Availability suspension with consentration PGA 5 % and carbopol P 934 3 % is perfect formula. Keywords: Formulation, chloramphenicol, Suspending Agent PulvisGummi Arabici, Carbopol P 934
| Item Type: | Thesis (Karya Tulis Ilmiah) |
|---|---|
| Uncontrolled Keywords: | Formulation, chloramphenicol, Suspending Agent PulvisGummi Arabici, Carbopol P 934 |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Prodi D3 Farmasi |
| Depositing User: | magdalena kartika ningsih |
| Date Deposited: | 10 Oct 2019 04:26 |
| Last Modified: | 10 Oct 2019 04:26 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/1718 |
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