UJI EFEK ANALGESIK INFUSA DAUN PEPAYA (Carica pepaya L.) TERHADAP MENCIT PUTIH JANTAN (Mus musculus) YANG DIINDUKSI ASAM ASETAT

Lestari, Lestari (2016) UJI EFEK ANALGESIK INFUSA DAUN PEPAYA (Carica pepaya L.) TERHADAP MENCIT PUTIH JANTAN (Mus musculus) YANG DIINDUKSI ASAM ASETAT. Karya Tulis Ilmiah thesis, Universitas Setia Budi Surakarta.

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Abstract

Papaya (Carica papaya L) is a plant that grows in tropical region can be used as a drug to treat various diseases including analgesics. This research purposed the analgesic effect of papaya infusion on the white male mice induced by acetic acid and to find the most effective dose. Papaya leaves extracted infundation method. The test method Sigmund analgesic method with chemical stimulation to induce pain. Test animals were divided into 5 groups, each group consisted of 4 mice. Group I (negative control) distilled water, group II (positive control) paracetamol, group III (infusion of leave papaya dose of 0.6 g / kg), Group IV (intravenous doses of papaya leaf 1.2 g / kg) and group V (papaya leaf infusion dose of 2.4 g / kg). The number of writhing is counted every 10 minutes for 60 minutes. Data have been obtained then analyzed statistically using ANOVA with a level of 95% followed by Dunnett T3 tests to determine analgesic% power. The results showed that the infusion of papaya leaves has an analgesic effects on white male mice. Dose infusion of papaya leaves the most effective analgesic effect is dose of 1.2 g / kg with analgesic % power 48,21%. Keywords: Papaya leaves, infundation, analgesic.

Item Type: Thesis (Karya Tulis Ilmiah)
Uncontrolled Keywords: Papaya leaves, infundation, analgesic.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi D3 Farmasi
Depositing User: magdalena kartika ningsih
Date Deposited: 10 Oct 2019 04:31
Last Modified: 10 Oct 2019 04:31
URI: http://repo.setiabudi.ac.id/id/eprint/1747

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