EFEK UMBI GARUT (Maranta arundinaceae Linn.) DALAM MENURUNKAN TINGKAT KEMERAHAN MUKOSA LAMBUNG TIKUS PUTIH JANTAN GALUR WISTAR YANG DIINDUKSI ASPIRIN

Gantur, Wilibaldus Yandri (2014) EFEK UMBI GARUT (Maranta arundinaceae Linn.) DALAM MENURUNKAN TINGKAT KEMERAHAN MUKOSA LAMBUNG TIKUS PUTIH JANTAN GALUR WISTAR YANG DIINDUKSI ASPIRIN. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Garut (Maranta arundinaceae Linn.) tuber was empirically used for gastritist drug. This research aimed to find out the effect of garut tuber in reducing the gastric mucous redness level of wistar strain male white rat induced with aspirin at dose 150 mg/Kg BW. This research employed post test-only control group design using 35 rats, aged 2-3 month divided into 6 groups. The groups were: K I (aqua destilata, 2.5 mL/200 g BW), K II (aqua destilata, 2.5 mL/200gBW), K III (sucralfat, 0.18 mL/200g BW), K IV (garut tuber extract), K V (garut starch suspension 2.5 mL/200gBW) and K VI (garut starch porridge 2.5 mL/200 BW) per oral. Before treatment all rats were fasted for 24 hours. After 10 minutes treatment, groups II, III, IV, V, and VI were induced with aspirin at dose 150 mg/Kg BW and left for 24 hours. Then, they were slaughtered, their stomach was examined for the redness level of mucous and scored. The data obtained was analyzed using Kruskall-Wallis, followed with Mann-Whitney Tests at confidence interval 95%. The result of research showed that the garut tuber extract, suspension and starch porridge had the effect of reducing the gastric mucous redness level in the Wistar strain of male white rats induced with aspirin at dose 150 mg/Kg BW. Keywords: extract, suspension, porridge, garut tuber, gastric mucous redness.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: extract, suspension, porridge, garut tuber, gastric mucous redness.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 20 Feb 2020 02:53
Last Modified: 20 Feb 2020 02:53
URI: http://repo.setiabudi.ac.id/id/eprint/2893

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