PERBANDINGAN EFEKTIVITAS SUSU PROBIOTIK KAMBING DAN SUSU PROBIOTIK SAPI TERHADAP KADAR SGOT DAN SGPT MENCIT YANG TERPAPAR FORMALIN

Rahman, Imron Rosyadi (2014) PERBANDINGAN EFEKTIVITAS SUSU PROBIOTIK KAMBING DAN SUSU PROBIOTIK SAPI TERHADAP KADAR SGOT DAN SGPT MENCIT YANG TERPAPAR FORMALIN. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

The existence of formaldehyde in the body can cause a drastic decrease of antioxidants, so that leads to causing oxidative stress which resulted in oxidative damage to the damage and death liver cell. The purpose of this study is determine the activity of cow’s and goat’s milk with probiotic to SGOT and SGPT levels mice’s liver was induced by formaldehyde and to find out which is more effective between of them to decrease SGOT and SGPT levels. This study used six groups of test animals consisting of cow’s milk with probiotic (SPS), goat’s milk with probiotic (SPK), cow’s milk (SS), goat’s milk (SK), normal control (A), dan formalin control (F). Probiotic bacteria in milk is inoculated by three types LAB from yoghurt starter. SGOT and SGPT levels in the mice serum was determined by Spectrophotometer UV-1201V (SHIMADZU). SGOT data analyzed with Kruskal Wallis & Mann Whitney Test, and SGPT data analyzed with One Way Anova & Post Hoc (SNK). SPK and SPS group have activity to SGOT and SGPT levels, and the most effective to decrease SGOT and SGPT levels is SPK group. It is based on the results of analysis SGOT and SGPT activity are SPK (21,6860 U/L and 17,8600 U/L), SPS (22,3920 U/L and 18,5000 U/L), A (22,7980 U/L and 18,7980 U/L), SK (24,5520 U/L and 20,8620 U/L), SS (25,4860 U/L and 22,7780 U/L), F (34,0760 U/L and 28,4120 U/L). Keywords: probiotic milk, formalin, cow's milk, goat's milk, SGOT, SGPT

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: probiotic milk, formalin, cow's milk, goat's milk, SGOT, SGPT
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: B Supri Yadi
Date Deposited: 20 Nov 2019 04:52
Last Modified: 20 Nov 2019 04:52
URI: http://repo.setiabudi.ac.id/id/eprint/2913

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