UJI AKTIVITAS ANTIDEPRESAN KOMBINASI INFUSA DAUN PUTRI MALU (Mimosa pudica L.) DENGAN BIJI PETAI (Parkia speciosa Hassk) TERHADAP MENCIT PUTIH JANTAN (Mus musculus)

Purnomo, Hery (2013) UJI AKTIVITAS ANTIDEPRESAN KOMBINASI INFUSA DAUN PUTRI MALU (Mimosa pudica L.) DENGAN BIJI PETAI (Parkia speciosa Hassk) TERHADAP MENCIT PUTIH JANTAN (Mus musculus). Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Leaves of putri malu (Mimosa pudica L.) and biji petai (Parkia speciosa Hassk) have various properties one of them as an antidepressant. Mimosin on the leaves of putri malu as well as tryptophan and vitamin B6 on biji petai are efficacious as antidepressant compounds. This study aimed to know the effects of antidepressants in combination infusa Mimosa pudica L. and Parkia speciosa Hassk. and the effective doses of combination infusa. The antidepressant method was used Tail suspension test (TST) to assess the immobility time on each treatment. Animal testing in the form of 30 mice were divided into 6 groups, they are negative control aquadest as much as ml/20g 0,5 BW mice, positive control Tofranil 0,065mg/20g BW mice, the formulation I a single dose infusa putri malu leaves 39mg/20g BW mice, formulation II combination infusa of putri malu leaves 19,5 mg with biji petai 26mg/20g BW mice, formulation III combination infusa of putri malu leaves 29,2 mg with biji petai 13mg/20g BW mice, formulation IV combination infusa of putri malu leaves 9,75 mg with biji petai 39mg/20g BW mice. Giving aquadest and infusa was done orally. All groups were conducted TST about 6 minutes and measured immobility time. Immobility time was analyzed by ANOVA test. The result of test showed that combination infusa of putri malu leaves with biji petai have antidepressant effect. This things showed that formulation III with combination dosage infusa of putri malu leaves 29,2 mg with biji petai 13mg/20g BW mice have antidepressant effect is most effective between the other treatment. Keyword : antidepressant, putri malu- petai, Tail Suspension Test

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	antidepressant, putri malu- petai, Tail Suspension Test
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	magdalena kartika ningsih
Date Deposited:	21 Feb 2020 03:44
Last Modified:	21 Feb 2020 03:44
URI:	http://repo.setiabudi.ac.id/id/eprint/2955

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